Systemic sclerosis (SSc) is an autoimmune disease characterised by microvasculopathy,
immune dysregulation, and skin and visceral organ fibrosis. Every year novel insights into …

Early diagnosis and clinical management of SSc and SSc-related complications are still
challenging for rheumatologists. The development of predictive models and tools using …

Primary Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by
lymphocytic infiltration and damage of exocrine salivary and lacrimal glands. The etiology of …

The heterogeneity of systemic lupus erythematosus (SLE) can be explained by epigenetic
alterations that disrupt transcriptional programs mediating environmental and genetic risk …

Objective Systemic sclerosis (SSc) is a multifactorial autoimmune fibrotic disorder involving
complex rewiring of cell‐intrinsic and cell‐extrinsic signaling coexpression networks …

Copy number (CN) polymorphisms of complement C4 play distinct roles in many conditions,
including immune-mediated diseases. We investigated the association of C4 CN with …

Systemic sclerosis (SSc), also known as scleroderma, is an autoimmune-related connective
tissue disease with a complex and unknown pathophysiological mechanism with genes …

Systemic sclerosis (SSc) is a progressive autoimmune disorder that mainly affects the skin.
There are other clinical manifestations as renal, pulmonary, cardiovascular, and …

Objective The heterogeneity of systemic lupus erythematosus (SLE) can be explained by
epigenetic alterations that disrupt transcriptional programs mediating environmental and …

Systemic sclerosis, or scleroderma (SSc), is a complex immunemediated inflammatory
disorder. SSc pathogenesis involves a triad of factors: immunological imbalance …