Fiber photometry is a key technique for characterizing brain-behavior relationships in vivo.
Initially, it was primarily used to report calcium dynamics as a proxy for neural activity via …

Impaired sleep is a common aspect of aging and often precedes the onset of Alzheimer's
disease. Here, we compare the effects of sleep deprivation in young wild-type mice and their …

Neurotransmitter analysis plays a pivotal role in diagnosing and managing
neurodegenerative diseases, often characterized by disturbances in neurotransmitter …

Striatal dopamine (DA) release has long been linked to reward processing, but it remains
controversial whether DA release reflects costs or benefits and how these signals vary with …

Substantial evidence has shown that the Circadian Locomotor Output Cycles Kaput (Clock)
gene is a core transcription factor of circadian rhythms that regulates dopamine (DA) …

Altered interaction between striatonigral dopaminergic (DA) inputs and local acetylcholine
(ACh) in striatum has long been hypothesized to play a central role in the pathophysiology of …

The role of the dynorphin/kappa opioid receptor (KOR) system in dopamine (DA) regulation
has been extensively investigated. KOR activation reduces extracellular DA concentrations …

In recent years, fluorescent sensors are enjoying a surge of popularity in the field of
neuroscience. Through the development of novel genetically encoded sensors as well as …

Background: Amphetamine is a commonly abused psychostimulant that increases synaptic
catecholamine levels and impairs executive functions. However, it is unknown how acute …

Altered interaction between striatonigral dopaminergic (DA) inputs and local acetylcholine
(ACh) in striatum has long been hypothesized to play a central role in dystonia …