Borneol: a promising monoterpenoid in enhancing drug delivery across various physiological barriers
M Kulkarni, N Sawant, A Kolapkar, A Huprikar… - AAPS …, 2021 - Springer
Incorporation of permeation enhancers is one of the most widely employed approaches for
delivering drugs across biological membranes. Permeation enhancers aid in delivering …
delivering drugs across biological membranes. Permeation enhancers aid in delivering …
Emerging insights on drug delivery by fatty acid mediated synthesis of lipophilic prodrugs as novel nanomedicines
Many drug molecules that are currently in the market suffer from short half-life, poor
absorption, low specificity, rapid degradation, and resistance development. The design and …
absorption, low specificity, rapid degradation, and resistance development. The design and …
Reconstituted high density lipoprotein (rHDL), a versatile drug delivery nanoplatform for tumor targeted therapy
Y Mei, L Tang, Q Xiao, Z Zhang, Z Zhang… - Journal of Materials …, 2021 - pubs.rsc.org
rHDL is a synthesized drug delivery nanoplatform exhibiting excellent biocompatibility,
which possesses most of the advantages of HDL. rHDL shows almost no toxicity and can be …
which possesses most of the advantages of HDL. rHDL shows almost no toxicity and can be …
Lipophilic 5-fluorouracil prodrug encapsulated xylan-stearic acid conjugates nanoparticles for colon cancer therapy
In this study, self-assembled nanoparticles based on amphiphilic xylan-stearic acid (Xyl-SA)
conjugates have been developed for the efficient delivery of 5-fluorouracil (5-FU) in cancer …
conjugates have been developed for the efficient delivery of 5-fluorouracil (5-FU) in cancer …
A green and highly efficient method to deliver hydrophilic polyphenols of Salvia miltiorrhiza and Carthamus tinctorius for enhanced anti-atherosclerotic effect via metal …
Q Tang, Y Yi, Y Chen, Z Zhuang, F Wang… - Colloids and Surfaces B …, 2022 - Elsevier
Salvia miltiorrhiza and Carthamus tinctorius are traditional Chinese medicines that have
been widely used for the treatment of cardiovascular disease. Salvianic acid A (SAA) …
been widely used for the treatment of cardiovascular disease. Salvianic acid A (SAA) …
Advances and perspectives on pharmacological activities and mechanisms of the monoterpene borneol
X Hu, Y Yan, W Liu, J Liu, T Fan, H Deng, Y Cai - Phytomedicine, 2024 - Elsevier
Background Borneol, a highly lipid-soluble bicyclic terpene mainly extracted from plants, is
representative of monoterpenoids. Modern medicine has established that borneol exhibits a …
representative of monoterpenoids. Modern medicine has established that borneol exhibits a …
Supramolecular dendrimers based novel platforms for effective oral delivery of therapeutic moieties
Dendrimers are globular three-dimensional synthetic macromolecules that are highly
branched with a definite molecular weight. The distinct physicochemical properties and …
branched with a definite molecular weight. The distinct physicochemical properties and …
Opportunities and challenges of fatty acid conjugated therapeutics
Instability, poor cellular uptake and unfavorable pharmacokinetics and biodistribution of
many therapeutic molecules require modification in their physicochemical properties. The …
many therapeutic molecules require modification in their physicochemical properties. The …
Transporter effects on cell permeability in drug delivery
Introduction: The role of drug transporters as one of the determinants of cellular drug
permeability has become increasingly evident. Despite the lipophilicity of a drug molecule …
permeability has become increasingly evident. Despite the lipophilicity of a drug molecule …