X-ray free-electron lasers provide femtosecond-duration pulses of hard X-rays with a peak
brightness approximately one billion times greater than is available at synchrotron radiation …

The advent of the X-ray free electron laser (XFEL) in the last decade created the discipline of
serial crystallography but also the challenge of how crystal samples are delivered to X-ray …

To advance microfluidic integration, we present the use of two-photon additive
manufacturing to fold 2D channel layouts into compact free-form 3D fluidic circuits with …

The European X-ray Free-Electron Laser (FEL) became the first operational high-repetition-
rate hard X-ray FEL with first lasing in May 2017. Biological structure determination has …

Crystallography has made a notable contribution to our knowledge of structural biology. For
traditional crystallography experiments, the growth of crystals with large size and high …

Ultra-bright femtosecond X-ray pulses generated by X-ray free-electron lasers (XFELs) can
be used to image high-resolution structures without the need for crystallization. For this …

Serial femtosecond crystallography (SFX) with X-ray free electron lasers (XFELs) is an
emerging field for structural biology. One of its major impacts lies in the ability to reveal the …

A numerical simulation infrastructure capable of calculating the flow of gas and the
trajectories of particles through an aerodynamic lens injector is presented. The simulations …

A novel methodology for measuring gas flow from small orifices or nozzles into vacuum is
presented. It utilizes a high-intensity femtosecond laser pulse to create a plasma within the …

In single-particle imaging experiments, beams of individual nanoparticles are exposed to
intense pulses of X-rays from free-electron lasers to record diffraction patterns of single …