Clinical advances and perspectives in targeted radionuclide therapy

N Lepareur, B Ramée, M Mougin-Degraef… - Pharmaceutics, 2023 - mdpi.com
Targeted radionuclide therapy has become increasingly prominent as a nuclear medicine
subspecialty. For many decades, treatment with radionuclides has been mainly restricted to …

[HTML][HTML] A review of advances in the last decade on targeted cancer therapy using 177Lu: Focusing on 177Lu produced by the direct neutron activation route

R Chakravarty, S Chakraborty - American Journal of Nuclear …, 2021 - ncbi.nlm.nih.gov
Abstract Lutetium-177 [T½= 6.76 d; E β (max)= 0.497 MeV; maximum tissue range~ 2.5 mm;
208 keV γ-ray] is one of the most important theranostic radioisotope used for the …

Advancements in the development of radiopharmaceuticals for nuclear medicine applications in the treatment of bone metastases

MR Dyer, Z Jing, K Duncan, J Godbe… - Nuclear Medicine and …, 2024 - Elsevier
Bone metastases are a painful and complex condition that overwhelmingly impacts the
prognosis and quality of life of cancer patients. Over the years, nuclear medicine has made …

Evaluation of photon, proton, and alpha interaction parameters of EDTMPLu and MDPLu medications used for some bone cancer

AMA Mostafa, MAM Uosif, SAM Issa… - Radiation Physics and …, 2024 - Elsevier
In this study, we explore the interactions of photons, protons, and alpha with matter in the
context of two drugs, MDPLu and EDTMPLu, delving into the interesting field of radiation …

Current clinical application of lutetium‑177 in solid tumors

T Niu, M Fan, B Lin, F Gao… - Experimental and …, 2024 - spandidos-publications.com
Radionuclide‑based therapy represents a novel treatment regimen for tumors. Among these
therapies, lutetium‑177 (177 Lu) has gained significant attention due to its stability and …

Theragnostic Radionuclide Pairs for Prostate Cancer Management: 64Cu/67Cu, Can Be a Budding Hot Duo

A Chhabra, ML Thakur - Biomedicines, 2022 - mdpi.com
Prostate cancer (PCa) is one of the preeminent causes of mortality in men worldwide.
Theragnostic, a combination of therapy and diagnostic, using radionuclide pairs to diagnose …

Targeted Radiopharmaceutical Therapy for Bone Metastases

S Mahajan, S Gavane, N Pandit-Taskar - Seminars in Nuclear Medicine, 2024 - Elsevier
Radiopharmaceutical approaches for targeting bone metastasis have traditionally focused
on palliation of pain. Several agents have been clinically used over the last several decades …

Efficacy and Safety of 177Lu-DOTA-IBA in Tumor Bone Metastasis Treatment: A Prospective Clinical Trial

T Xu, Y Wang, G Liu, H Li, G Qu, X Zhang… - Clinical nuclear …, 2025 - journals.lww.com
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[图书][B] Molecular Imaging and Targeted Therapy

S Vallabhajosula - 2023 - Springer
The cell is the basic unit of life in all forms of living organisms, from the smallest bacterium to
the most complex animal. On the basis of microscopic and biochemical differences, living …

Recent Advances and Future Perspectives in Radiolabeled Antibody Fragments for Breast Cancer Molecular Imaging

R Gerami, MA Altafi, Z Shahpar, E Izadpanah… - Frontiers in Biomedical …, 2023 - fbt.tums.ac.ir
Breast Cancer (BC) is the leading cause of cancer-related deaths in women and the most
common cancer worldwide. It is classified based on its anatomical origin, the presence of …