Fibrosis is a pathological process caused by abnormal wound healing response, which
often leads to excessive deposition of extracellular matrix, distortion of organ architecture …

Keloids are scars that extend beyond the margins of an insulting cutaneous injury. Keloids
are often thought to be primarily a cosmetic issue, as they are typically quite raised and …

Background Fibrosis with unrelieved chronic inflammation is an important pathological
change in keloids. Mitochondrial autophagy plays a crucial role in reducing inflammation …

Keloid is an abnormal fibrotic disease after cutaneous injury characterized by exaggerated
scar tissue formation, which often extends beyond the boundaries of the original wound …

Keloids are skin fibroproliferative disorders, resulting from abnormal healing of deep
cutaneous injuries. Cryosurgery, the most common treatment for keloids, causes skin …

Abstract Background Exosomes (Exos) and their contained microRNAs (miRNAs) have
been emergingly recognized as key regulators in spanning biological processes, including …

Background: Keloids are benign fibrous growths that are caused by excessive tissue build-
up. Severe keloids exert more significant effects on patients' quality of life than do mild …

Significance: Laser use has become part of the gold standard of treatment as an effective
adjuvant in multimodal therapy for pathologic scarring caused by burns, trauma, acne, and …

Keloid is a disease in which fibroblasts abnormally proliferate and synthesize excessive
amounts of extracellular matrix, including collagen and fibronectin, during the healing …

Background Cutaneous scaring is an inevitable consequence following burns deeper than
the dermis. Although burn scars from more superficial injuries can resemble normal skin in …