S Sui, S Xu, D Pang - Pharmacology & therapeutics, 2022 - Elsevier
Breast cancer has become a serious threat to women's health. Cancer progression is mainly derived from resistance to apoptosis induced by procedures or therapies. Therefore, new …
M Gray, AK Turnbull, C Ward, J Meehan… - Radiation …, 2019 - Springer
Background Radiotherapy plays an important role in the multimodal treatment of breast cancer. The response of a breast tumour to radiation depends not only on its innate …
M Van Hartskamp, S Consoli, W Verhaegh… - Interactive journal of …, 2019 - i-jmr.org
The idea of artificial intelligence (AI) has a long history. It turned out, however, that reaching intelligence at human levels is more complicated than originally anticipated. Currently, we …
Endocrine therapy is important for management of patients with estrogen receptor (ER)– positive breast cancer; however, positive ER staining does not reliably predict therapy …
GF van Wigcheren, J Cuenca-Escalona… - Journal of Biological …, 2023 - ASBMB
Imbalanced immune responses are a prominent hallmark of cancer and autoimmunity. Myeloid cells can be overly suppressive, inhibiting protective immune responses or inactive …
Combined cellular and humoral host immune response determine the clinical course of a viral infection and effectiveness of vaccination, but currently the cellular immune response …
The phosphoinositide 3-kinase (PI3K) growth factor signaling pathway plays an important role in embryonic development and in many physiological processes, for example the …
Precision treatment of cancer requires knowledge on active tumor driving signal transduction pathways to select the optimal effective targeted treatment. Currently only a …
Background Oestrogen receptor (ER) expression is a prognostic biomarker in endometrial cancer (EC). However, expression does not provide information about the functional activity …