For several decades, the reactive gliosis that occurs after an injury to the CNS has been
considered one of the major impediments to axonal regeneration. Nevertheless, recent …

Based upon neurophysiologic, neuroanatomic, and neuroimaging studies conducted over
the past two decades, the cerebral cortex can now be viewed as functionally and structurally …

Stroke is the leading cause of adult disability. Yet there is a limited degree of recovery in this
disease. One of the mechanisms of recovery is the formation of new connections in the brain …

Ischemic stroke produces cell death and disability, and a process of repair and partial
recovery. Plasticity within cortical connections after stroke leads to partial recovery of …

The ability of the adult brain to form new connections in areas denervated by a lesion
(axonal sprouting) is more widespread than previously thought, but mechanisms remain …

Voluntary exercise, treadmill activity, skills training, and forced limb use have been utilized in
animal studies to promote brain plasticity and functional change. Motor enrichment may …

Unilateral lesions of the forelimb area of the sensorimotor cortex in adult rats resulted in time-
dependent increases in the number of synapses per neuron and the volume and membrane …

The subventricular zone (SVZ) generates the largest number of migratory cells in the adult
brain. SVZ neuroblasts migrate to the olfactory bulbs (OB) in the adult, whereas during …

We compared the effects of three models of permanent ischemia, as well as cortical
aspiration, on behaviour and brain morphology. Rats received a stroke either by …

Abnormalities of proteins involved in neurotransmission and neural plasticity at synapses
are reported in schizophrenia, and may be markers of dysregulated neural connectivity in …