Melatonin, a full service anti-cancer agent: inhibition of initiation, progression and metastasis
There is highly credible evidence that melatonin mitigates cancer at the initiation,
progression and metastasis phases. In many cases, the molecular mechanisms …
progression and metastasis phases. In many cases, the molecular mechanisms …
[HTML][HTML] Melatonin for the prevention and treatment of cancer
Y Li, S Li, Y Zhou, X Meng, JJ Zhang, DP Xu, HB Li - Oncotarget, 2017 - ncbi.nlm.nih.gov
The epidemiological studies have indicated a possible oncostatic property of melatonin on
different types of tumors. Besides, experimental studies have documented that melatonin …
different types of tumors. Besides, experimental studies have documented that melatonin …
Melatonin and its ubiquitous anticancer effects
Abstract Melatonin (N-acetyl-5-methoxy-tryptamine), which is generally considered as
pleiotropic and multitasking molecule, secretes from pineal gland at night under normal light …
pleiotropic and multitasking molecule, secretes from pineal gland at night under normal light …
Melatonin: a multitasking molecule
Abstract Melatonin (N-acetyl-5-methoxytryptamine) has revealed itself as an ubiquitously
distributed and functionally diverse molecule. The mechanisms that control its synthesis …
distributed and functionally diverse molecule. The mechanisms that control its synthesis …
Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling
Evidence is accumulating regarding the importance of circadian core oscillators, several
associated factors, and melatonin signaling in the maintenance of health. Dysfunction of …
associated factors, and melatonin signaling in the maintenance of health. Dysfunction of …
Role and therapeutic potential of melatonin in various type of cancers
S Gurunathan, M Qasim, MH Kang… - OncoTargets and …, 2021 - Taylor & Francis
Cancer is a large group of diseases and the second leading cause of death worldwide.
Lung, prostate, colorectal, stomach, and liver cancers are the most common types of cancer …
Lung, prostate, colorectal, stomach, and liver cancers are the most common types of cancer …
Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in …
Inflammation is a complex phenomenon involving multiple cellular and molecular
interactions which must be tightly regulated. Cyclooxygenase-2 (COX) is the key enzyme …
interactions which must be tightly regulated. Cyclooxygenase-2 (COX) is the key enzyme …
Basic mechanisms involved in the anti-cancer effects of melatonin
MD Mediavilla, EJ Sanchez-Barcelo… - Current medicinal …, 2010 - ingentaconnect.com
It is commonly accepted that melatonin (N-acetyl-5-methoxytryptamine), the most relevant
pineal secretory product, has oncostatic properties in a wide variety of tumors and …
pineal secretory product, has oncostatic properties in a wide variety of tumors and …
Molecular mechanisms of the pro-apoptotic actions of melatonin in cancer: a review
M Bizzarri, S Proietti, A Cucina… - Expert opinion on …, 2013 - Taylor & Francis
Introduction: Compelling evidence has highlighted the complex pleiotropic functions elicited
by the melatonin in cancer cells. Melatonin behaves as a 'smart killer', ie, modulating anti …
by the melatonin in cancer cells. Melatonin behaves as a 'smart killer', ie, modulating anti …
The circadian timing system in clinical oncology
The circadian timing system (CTS) controls several critical molecular pathways for cancer
processes and treatment effects over the 24 hours, including drug metabolism, cell cycle …
processes and treatment effects over the 24 hours, including drug metabolism, cell cycle …