Glutathione S-transferase: A keystone in Parkinson's disease pathogenesis and therapy
P Padhan, N Kumar, S Verma - Molecular and Cellular Neuroscience, 2024 - Elsevier
Parkinson's disease is a progressive neurodegenerative disorder that predominantly affects
motor function due to the loss of dopaminergic neurons in the substantia nigra. It presents …
motor function due to the loss of dopaminergic neurons in the substantia nigra. It presents …
Histone Deacetylation in Alzheimer's Diseases (AD); Hope or Hype
NH Ateya, SF Al-Taie, SA Jasim, S Uthirapathy… - Cell Biochemistry and …, 2025 - Springer
Histone acetylation is the process by which histone acetyltransferases (HATs) add an acetyl
group to the N-terminal lysine residues of histones, resulting in a more open chromatin …
group to the N-terminal lysine residues of histones, resulting in a more open chromatin …
Design, synthesis, and biological evaluation of novel AAK1/HDACs dual inhibitors against SARS-CoV-2 entry
ND Mao, Y Xu, X Yao, Y Gao, Z Hui, H Che, C Wang… - Bioorganic …, 2024 - Elsevier
Abstract AP2-associated protein kinase 1 (AAK1) is a crucial regulator of clathrin-mediated
endocytosis, involved in various cellular processes, including viral infection. Histone …
endocytosis, involved in various cellular processes, including viral infection. Histone …
[HTML][HTML] Fluoride Alters Gene Expression via Histone H3K27 Acetylation in Ameloblast-like LS8 Cells
S Yamashita, M Okamoto, M Mendonca… - International Journal of …, 2024 - mdpi.com
Excessive fluoride ingestion during tooth development can cause dental fluorosis.
Previously, we reported that fluoride activates histone acetyltransferase (HAT) to acetylate …
Previously, we reported that fluoride activates histone acetyltransferase (HAT) to acetylate …