Breakthrough in CRISPR/Cas system: Current and future directions and challenges

A Ali, MM Zafar, Z Farooq, SR Ahmed… - Biotechnology …, 2023 - Wiley Online Library
Targeted genome editing (GE) technology has brought a significant revolution in fictional
genomic research and given hope to plant scientists to develop desirable varieties. This …

Challenges to develop nitrogen-fixing cereals by direct nif-gene transfer

L Curatti, LM Rubio - Plant Science, 2014 - Elsevier
Some regions of the developing world suffer low cereal production yields due to low fertilizer
inputs, among other factors. Biological N 2 fixation, catalyzed by the prokaryotic enzyme …

[图书][B] The Chlamydomonas Sourcebook: Introduction to Chlamydomonas and Its Laboratory Use: Volume 1

EH Harris - 2009 - books.google.com
Dr. Harris has played a major role in the development of this organism as a model system.
Her previous version of the Chlamydomonas Sourcebook which published in 1989, has …

[HTML][HTML] Mitochondrial ATP synthase disorders: molecular mechanisms and the quest for curative therapeutic approaches

R Kucharczyk, M Zick, M Bietenhader, M Rak… - … et Biophysica Acta (BBA …, 2009 - Elsevier
In mammals, the majority of cellular ATP is produced by the mitochondrial F1FO-ATP
synthase through an elaborate catalytic mechanism. While most subunits of this enzymatic …

Witnessing genome evolution: experimental reconstruction of endosymbiotic and horizontal gene transfer

R Bock - Annual review of genetics, 2017 - annualreviews.org
Present day mitochondria and plastids (chloroplasts) evolved from formerly free-living
bacteria that were acquired through endosymbiosis more than a billion years ago …

Optimized production of a bioactive human recombinant protein from the microalgae Chlamydomonas reinhardtii grown at high density in a fed-batch bioreactor

Y Torres-Tiji, FJ Fields, Y Yang, V Heredia, SJ Horn… - Algal Research, 2022 - Elsevier
Microalgae have been identified as an alternative platform to produce high-quality biomass
and subsequent bioproducts, such as foods, feeds, nutritional supplements, recombinant …

Allotopic expression of mitochondrial-encoded genes in mammals: achieved goal, undemonstrated mechanism or impossible task?

E Perales-Clemente, P Fernandez-Silva… - Nucleic acids …, 2011 - academic.oup.com
Mitochondrial-DNA diseases have no effective treatments. Allotopic expression—synthesis
of a wild-type version of the mutated protein in the nuclear-cytosolic compartment and its …

Current progress with mammalian models of mitochondrial DNA disease

JB Stewart - Journal of Inherited Metabolic Disease, 2021 - Wiley Online Library
Mitochondrial disorders make up a large class of heritable diseases that cause a broad
array of different human pathologies. They can affect many different organ systems, or …

Dual Functions of Mss51 Couple Synthesis of Cox1 to Assembly of Cytochrome c Oxidase in Saccharomyces cerevisiae Mitochondria

X Perez-Martinez, CA Butler… - Molecular biology of …, 2009 - Am Soc Cell Biol
Functional interactions of the translational activator Mss51 with both the mitochondrially
encoded COX1 mRNA 5′-untranslated region and with newly synthesized unassembled …

Mitochondrial-Nuclear Epistasis Contributes to Phenotypic Variation and Coadaptation in Natural Isolates of Saccharomyces cerevisiae

S Paliwal, AC Fiumera, HL Fiumera - Genetics, 2014 - academic.oup.com
Mitochondria are essential multifunctional organelles whose metabolic functions,
biogenesis, and maintenance are controlled through genetic interactions between …