Mechanisms of germ cell specification across the metazoans: epigenesis and preformation

CG Extavour, M Akam - 2003 - journals.biologists.com
Germ cells play a unique role in gamete production, heredity and evolution. Therefore, to
understand the mechanisms that specify germ cells is a central challenge in developmental …

The power of the 3′ UTR: translational control and development

S Kuersten, EB Goodwin - Nature Reviews Genetics, 2003 - nature.com
Many crucial decisions, such as the location and timing of cell division, cell-fate
determination, and embryonic axes establishment, are made in the early embryo, a time in …

[HTML][HTML] Liquid-to-solid phase transition of oskar ribonucleoprotein granules is essential for their function in Drosophila embryonic development

M Bose, M Lampe, J Mahamid, A Ephrussi - Cell, 2022 - cell.com
Asymmetric localization of oskar ribonucleoprotein (RNP) granules to the oocyte posterior is
crucial for abdominal patterning and germline formation in the Drosophila embryo. We show …

Moving messages: the intracellular localization of mRNAs

D St Johnston - Nature reviews Molecular cell biology, 2005 - nature.com
Abstract mRNA localization is a common mechanism for targeting proteins to regions of the
cell where they are required. It has an essential role in localizing cytoplasmic determinants …

Cell turnover and adult tissue homeostasis: from humans to planarians

J Pellettieri, AS Alvarado - Annu. Rev. Genet., 2007 - annualreviews.org
Many fully developed metazoan tissues remain in a state of flux throughout life. During
physiological cell turnover, older differentiated cells are typically eliminated by apoptosis …

[HTML][HTML] Synaptic protein synthesis associated with memory is regulated by the RISC pathway in Drosophila

SI Ashraf, AL McLoon, SM Sclarsic, S Kunes - Cell, 2006 - cell.com
Long-lasting forms of memory require protein synthesis, but how the pattern of synthesis is
related to the storage of a memory has not been determined. Here we show that neural …

Signs of change? At‐home and breadwinner parents' housework and child‐care time

N Chesley, S Flood - Journal of Marriage and Family, 2017 - Wiley Online Library
Abstract The authors analyze American Time Use Survey data to examine patterns in
domestic work among at‐home and breadwinner parents to gauge how time availability …

[HTML][HTML] Drosophila cup is an eIF4E binding protein that associates with Bruno and regulates oskar mRNA translation in oogenesis

A Nakamura, K Sato, K Hanyu-Nakamura - Developmental cell, 2004 - cell.com
Translational control is a critical process in the spatio-temporal restriction of protein
production. In Drosophila oogenesis, translational repression of oskar (osk) RNA during its …

Control of translation initiation in animals

NK Gray, M Wickens - Annual review of cell and developmental …, 1998 - annualreviews.org
▪ Abstract Regulation of translation initiation is a central control point in animal cells. We
review our current understanding of the mechanisms of regulation, drawing particularly on …

The importance of CELF control: molecular and biological roles of the CUG‐BP, Elav‐like family of RNA‐binding proteins

T Dasgupta, AN Ladd - Wiley Interdisciplinary Reviews: RNA, 2012 - Wiley Online Library
RNA processing is important for generating protein diversity and modulating levels of protein
expression. The CUG‐BP, Elav‐like family (CELF) of RNA‐binding proteins regulate several …