From the last two decades, phthalimide analogues received prime interest from scientists
due to its potent inhibitory action on different cancer‐causing receptors. A variety of …

Background: Privileged motifs are recurring in a wide range of biologically active
compounds that reach different pharmaceutical targets and pathways and could represent a …

Different types of thiosemicarbazone derivatives were designed and tested for their Drug-
Like Molecular (DLM) nature by using Lipinski and Veber rules. Subsequently, compounds …

The continued toll of COVID-19 has halted the smooth functioning of civilization on a global
scale. With a limited understanding of all the essential components of viral machinery and …

Constant emergence of drug-resistant Plasmodium falciparum warrants urgent need for
effective and inexpensive drugs. Herein, phthalimide (Pht) analogs possessing the bioactive …

Quinoline-isoniazid-phthalimide triads have been synthesised to assess their antiplasmodial
efficacy and cytotoxicity against chloroquine-resistant W2 strain of P. falciparum and Vero …

Malaria remains a serious problem in global public health, particularly widespread in South
America and in tropical regions of Africa and Asia. Chemotherapy is actually the only way to …

Phthalimide, a pharmacophore exhibiting diverse biological activities, holds a prominent
position in medicinal chemistry. In recent decades, numerous derivatives of phthalimide …

Malaria is among the leading causes of death worldwide. The emergence of Plasmodium
falciparum resistant strains with reduced sensitivity to the first line combination therapy and …

Phthalimide derivatives have been presenting several promising biological activities in the
literature, such as anti-inflammatory, analgesic, antitumor, antimicrobial and anticonvulsant …