[HTML][HTML] Metallodrug binding to serum albumin: Lessons from biophysical and structural studies
A Merlino - Coordination Chemistry Reviews, 2023 - Elsevier
Human serum albumin (HSA) plays a major role in the transport of metallodrugs, affecting
pharmacokinetics and pharmacodynamics of these molecules. This work highlights the …
pharmacokinetics and pharmacodynamics of these molecules. This work highlights the …
Kinetics of reactions of dirhodium and diruthenium paddlewheel tetraacetate complexes with nucleophilic protein sites: Computational Insights
I Tolbatov, A Marrone - Inorganic Chemistry, 2022 - ACS Publications
Recently, dirhodium and diruthenium paddlewheel complexes have drawn attention as
perspective anticancer drugs. In this study, the kinetics of reaction of typical paddlewheel …
perspective anticancer drugs. In this study, the kinetics of reaction of typical paddlewheel …
Effect of equatorial ligand substitution on the reactivity with proteins of paddlewheel diruthenium complexes: Structural studies
The paddlewheel [Ru2Cl (O2CCH3) 4] complex was previously reported to react with the
model protein hen egg white lysozyme (HEWL), forming adducts with two diruthenium …
model protein hen egg white lysozyme (HEWL), forming adducts with two diruthenium …
Dirhodium tetraacetate binding to a B-DNA double helical dodecamer probed by X-ray crystallography and mass spectrometry
The reaction of the cytotoxic compound dirhodium tetraacetate with a B-DNA double helical
dodecamer was studied by X-ray crystallography and mass spectrometry. The structure of …
dodecamer was studied by X-ray crystallography and mass spectrometry. The structure of …
Cross-Linked Crystals of Dirhodium Tetraacetate/RNase A Adduct Can Be Used as Heterogeneous Catalysts
Due to their unique coordination structure, dirhodium paddlewheel complexes are of interest
in several research fields, like medicinal chemistry, catalysis, etc. Previously, these …
in several research fields, like medicinal chemistry, catalysis, etc. Previously, these …