Molecular regulation of interferon antiviral response in fish

YB Zhang, JF Gui - Developmental & Comparative Immunology, 2012 - Elsevier
Interferon (IFN) response is the first line of host defense against virus infection. The recent
years have witnessed tremendous progress in understanding of fish IFN antiviral response …

Transcriptome analysis based on RNA-Seq in understanding pathogenic mechanisms of diseases and the immune system of fish: a comprehensive review

A Sudhagar, G Kumar, M El-Matbouli - International journal of molecular …, 2018 - mdpi.com
In recent years, with the advent of next-generation sequencing along with the development
of various bioinformatics tools, RNA sequencing (RNA-Seq)-based transcriptome analysis …

Ligand specificities of Toll-like receptors in fish: indications from infection studies

D Pietretti, GF Wiegertjes - Developmental & Comparative Immunology, 2014 - Elsevier
Toll like receptors (TLRs) are present in many different fish families from several different
orders, including cyprinid, salmonid, perciform, pleuronectiform and gadiform …

Transcriptomics in aquaculture: current status and applications

S Chandhini, VJ Rejish Kumar - Reviews in Aquaculture, 2019 - Wiley Online Library
Transcriptomics is the analysis of total RNA transcript in a cell, which gives a broad idea of
cellular processes that are active and dormant. Recent advancement in next‐generation …

Integrated application of transcriptomics and metabolomics provides insights into unsynchronized growth in pearl oyster Pinctada fucata martensii

R Hao, X Du, C Yang, Y Deng, Z Zheng… - Science of the Total …, 2019 - Elsevier
Similar to other marine bivalves, Pinctada fucata martensii presents unsynchronized growth,
which is one of the problems farmers currently face. However, the underlying mechanisms …

Transcriptome analysis revealed changes of multiple genes involved in immunity in Cynoglossus semilaevis during Vibrio anguillarum infection

X Zhang, S Wang, S Chen, Y Chen, Y Liu… - Fish & shellfish …, 2015 - Elsevier
Half-smooth tongue sole (Cynoglossus semilaevis) is one of the most valuable marine
aquatic species in Northern China. Given to the rapid development of aquaculture industry …

Transcriptome analysis reveals the host immune response upon LMBV infection in largemouth bass (Micropterus salmoides)

W Xu, Z Zhang, F Lai, J Yang, Q Qin, Y Huang… - Fish & Shellfish …, 2023 - Elsevier
Largemouth bass (Micropterus salmoides) is one of the important economical freshwater
aquaculture species in China. However, the outbreak of viral diseases always caused great …

Identification of orange-spotted grouper (Epinephelus coioides) interferon regulatory factor 3 involved in antiviral immune response against fish RNA virus

Y Huang, X Huang, J Cai, Z OuYang, S Wei… - Fish & shellfish …, 2015 - Elsevier
Abstract Interferon regulatory factor 3 (IRF3) is an important transcription factor which
regulates the expression of interferon (IFN) and IFN-stimulated genes (ISGs) following virus …

Entry of a novel marine DNA virus, Singapore grouper iridovirus, into host cells occurs via clathrin-mediated endocytosis and macropinocytosis in a pH-dependent …

S Wang, X Huang, Y Huang, X Hao, H Xu… - Journal of …, 2014 - Am Soc Microbiol
Iridoviruses are nucleocytoplasmic DNA viruses which cause great economic losses in the
aquaculture industry but also show significant threat to global biodiversity. However, a lack …

Molecular cloning, expression and functional analysis of ISG15 in orange-spotted grouper, Epinephelus coioides

X Huang, Y Huang, J Cai, S Wei, Z Ouyang… - Fish & Shellfish …, 2013 - Elsevier
Interferon-stimulated gene 15 (ISG15) is an ubiquitin homolog that is significantly induced by
type I interferons or viral infections. Groupers, Epinephelus spp. being maricultured in China …