IL-1 family cytokine regulation of vascular permeability and angiogenesis

E Fahey, SL Doyle - Frontiers in Immunology, 2019 - frontiersin.org
The IL-1 family of cytokines are well-known for their primary role in initiating inflammatory
responses both in response to and acting as danger signals. It has long been established …

[HTML][HTML] Tumor angiogenesis: MMP-mediated induction of intravasation-and metastasis-sustaining neovasculature

EI Deryugina, JP Quigley - Matrix Biology, 2015 - Elsevier
Metastasis is a distinct stage of cancer progression that requires the development of
angiogenic blood vessels serving as conduits for tumor cell dissemination. An accumulated …

The role of macrophage phenotype in vascularization of tissue engineering scaffolds

KL Spiller, RR Anfang, KJ Spiller, J Ng, KR Nakazawa… - Biomaterials, 2014 - Elsevier
Angiogenesis is crucial for the success of most tissue engineering strategies. The natural
inflammatory response is a major regulator of vascularization, through the activity of different …

The many facets of macrophages in rheumatoid arthritis

E Siouti, E Andreakos - Biochemical pharmacology, 2019 - Elsevier
Macrophages are central to the pathophysiology of rheumatoid arthritis (RA). They constitute
the main source of pro-inflammatory cytokines and chemokines such as TNF and IL-1β, they …

Structural, antioxidant, prebiotic and anti-inflammatory properties of pectic oligosaccharides hydrolyzed from okra pectin by Fenton reaction

YK Yeung, YR Kang, BR So, SK Jung, YH Chang - Food Hydrocolloids, 2021 - Elsevier
To elucidate optimum conditions for the production of pectic oligosaccharides (POSs) with
excellent antioxidant, prebiotic, and anti-inflammatory activities, okra pectin (OP) was …

Under the spotlight: mechanisms of photobiomodulation concentrating on blue and green light

H Serrage, V Heiskanen, WM Palin… - Photochemical & …, 2019 - pubs.rsc.org
Photobiomodulation (PBM) describes the application of light at wavelengths ranging from
400–1100 nm to promote tissue healing, reduce inflammation and promote analgesia …

NF-κB and AP-1 connection: mechanism of NF-κB-dependent regulation of AP-1 activity

S Fujioka, J Niu, C Schmidt, GM Sclabas… - … and cellular biology, 2004 - Am Soc Microbiol
Nuclear factor κB (NF-κB) and activator protein 1 (AP-1) transcription factors regulate many
important biological and pathological processes. Activation of NF-κB is regulated by the …

Canonical pathway of nuclear factor κB activation selectively regulates proinflammatory and prothrombotic responses in human atherosclerosis

C Monaco, E Andreakos, S Kiriakidis… - Proceedings of the …, 2004 - National Acad Sciences
Nuclear factor κB (NF-κB) activation has been observed in human atherosclerotic plaques
and is enhanced in unstable coronary plaques, but whether such activation has a protective …

Atrial cardiomyopathy: pathophysiology and clinical consequences

A Goette, U Lendeckel - Cells, 2021 - mdpi.com
Around the world there are 33.5 million patients suffering from atrial fibrillation (AF) with an
annual increase of 5 million cases. Most AF patients have an established form of an atrial …

Differential gene expression in human, murine, and cell line-derived macrophages upon polarization

KL Spiller, EA Wrona, S Romero-Torres, I Pallotta… - Experimental cell …, 2016 - Elsevier
The mechanisms by which macrophages control the inflammatory response, wound healing,
biomaterial-interactions, and tissue regeneration appear to be related to their activation …