Plant glycosides and glycosidases: a treasure-trove for therapeutics

K Kytidou, M Artola, HS Overkleeft… - Frontiers in plant …, 2020 - frontiersin.org
Plants contain numerous glycoconjugates that are metabolized by specific
glucosyltransferases and hydrolyzed by specific glycosidases, some also catalyzing …

Exploring the diversity of β-glucosidase: classification, catalytic mechanism, molecular characteristics, kinetic models, and applications

ME Erkanli, K El-Halabi, JR Kim - Enzyme and Microbial Technology, 2024 - Elsevier
High-value chemicals and energy-related products can be produced from biomass.
Biorefinery technology offers a sustainable and cost-effective method for this high-value …

Glucocerebrosidase: functions in and beyond the lysosome

DEC Boer, J van Smeden, JA Bouwstra… - Journal of clinical …, 2020 - mdpi.com
Glucocerebrosidase (GCase) is a retaining β-glucosidase with acid pH optimum
metabolizing the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose …

Comparative genomics reveal distinct potential of Tamlana sp. S12 for algal polysaccharide degradation

HF Xia, XY Jia, YX Zhou, ZJ Du, DS Mu… - Frontiers in Marine …, 2023 - frontiersin.org
Introduction Macroalgae contain various polysaccharides that serve as nutrient sources
Introduction: Macroalgae contain various polysaccharides that serve as nutrient sources for …

CLN3 deficiency leads to neurological and metabolic perturbations during early development

U Heins-Marroquin, RR Singh… - Life Science …, 2024 - life-science-alliance.org
Juvenile neuronal ceroid lipofuscinosis (or Batten disease) is an autosomal recessive, rare
neurodegenerative disorder that affects mainly children above the age of 5 yr and is most …

Advancements on the Multifaceted Roles of Sphingolipids in Hematological Malignancies

Y Raza, J Atallah, C Luberto - International Journal of Molecular Sciences, 2022 - mdpi.com
Dysregulation of sphingolipid metabolism plays a complex role in hematological
malignancies, beginning with the first historical link between sphingolipids and apoptosis …

Structural basis of the inhibition of GH1 β-glucosidases by multivalent pyrrolidine iminosugars

M Martinez-Bailen, E Jiménez-Ortega, AT Carmona… - Bioorganic …, 2019 - Elsevier
The synthesis of multivalent pyrrolidine iminosugars via CuAAC click reaction between
different pyrrolidine-azide derivatives and tri-or hexavalent alkynyl scaffolds is reported. The …

Dynamics of ligand binding to a rigid glycosidase

F Ben Bdira, CA Waudby, AN Volkov… - Angewandte Chemie …, 2020 - Wiley Online Library
The single‐domain GH11 glycosidase from Bacillus circulans (BCX) is involved in the
degradation of hemicellulose, which is one of the most abundant renewable biomaterials in …

OPEN ACCESS EDITED BY

J Liu, N Zeng, Q Chen, Y Cheng, Y Wang… - Multi-Omics Analysis …, 2023 - books.google.com
The 2020 global cancer statistics show that gastric cancer (GC) is the fifth most common
cancer, accounting for 5.6% of all cancers worldwide, and has the fourth highest mortality …

[PDF][PDF] Chemical biolog studies on retaining exo-β-glucosidases

Q Su - probe, 2023 - scholarlypublications …
In June 2016, he obtained his BSc degree. Afterwards, he continued his master studies in
Pharmacy at School of Pharmaceutical Sciences, Chongqing University, Chongqing, China …