Pathogenesis and prevention of intraventricular hemorrhage

P Ballabh - Clinics in perinatology, 2013 - pmc.ncbi.nlm.nih.gov
Intraventricular hemorrhage (IVH) is a major neurological complication of prematurity.
Pathogenesis of intraventricular hemorrhage is attributed to intrinsic fragility of germinal …

The expanding phenotype of COL4A1 and COL4A2 mutations: clinical data on 13 newly identified families and a review of the literature

MEC Meuwissen, DJJ Halley, LS Smit, MH Lequin… - Genetics in …, 2015 - nature.com
Two proα1 (IV) chains, encoded by COL4A1, form trimers that contain, in addition, a proα2
(IV) chain encoded by COL4A2 and are the major component of the basement membrane in …

COL4A1 and COL4A2 mutations and disease: insights into pathogenic mechanisms and potential therapeutic targets

DS Kuo, C Labelle-Dumais… - Human molecular …, 2012 - academic.oup.com
Heterotrimers composed of collagen type IV alpha 1 (COL4A1) and alpha 2 (COL4A2)
constitute one of the most abundant components of nearly all basement membranes …

COL4A1 Mutations as a Monogenic Cause of Cerebral Small Vessel Disease: A Systematic Review

S Lanfranconi, HS Markus - Stroke, 2010 - Am Heart Assoc
Background and Purpose—A number of single gene disorders can cause cerebral small
vessel disease. Mutations in the COL4A1 gene encoding the type IV collagen alpha 1 chain …

COL4A2 mutations impair COL4A1 and COL4A2 secretion and cause hemorrhagic stroke

M Jeanne, C Labelle-Dumais, J Jorgensen… - The American Journal of …, 2012 - cell.com
Collagen, type IV, alpha 1 (COL4A1) and alpha 2 (COL4A2) form heterotrimers and are
abundant components of basement membranes, including those of the cerebral vasculature …

Detection of binder gradients using impedance spectroscopy and their influence on the tortuosity of Li-ion battery graphite electrodes

R Morasch, J Landesfeind, B Suthar… - Journal of The …, 2018 - iopscience.iop.org
Drying battery electrodes at high rates leads to binder migration and has shown to affect the
mechanical as well as the electrochemical properties of Li-ion battery electrodes. Up to now …

Intraventricular hemorrhage in very preterm infants: a comprehensive review

V Gilard, A Tebani, S Bekri, S Marret - Journal of clinical medicine, 2020 - mdpi.com
Germinal matrix-intraventricular-intraparenchymal hemorrhage (GMH-IVH-IPH) is a major
complication of very preterm births before 32 weeks of gestation (WG). Despite progress in …

Genotype-phenotype correlations in pathology caused by collagen type IV alpha 1 and 2 mutations

M Jeanne, DB Gould - Matrix Biology, 2017 - Elsevier
Abstract COL4A1 and COL4A2 are extracellular matrix proteins that form heterotrimers and
are present in nearly all basement membranes in every organ. In the past decade, COL4A1 …

COL4A1 mutations in patients with sporadic late‐onset intracerebral hemorrhage

YC Weng, A Sonni, C Labelle‐Dumais… - Annals of …, 2012 - Wiley Online Library
Objective: Mutations in the type IV collagen alpha 1 gene (COL4A1) cause dominantly
inherited cerebrovascular disease. We seek to determine the extent to which COL4A1 …

COL4A1 Mutations Cause Ocular Dysgenesis, Neuronal Localization Defects, and Myopathy in Mice and Walker-Warburg Syndrome in Humans

C Labelle-Dumais, DJ Dilworth, EP Harrington… - PLoS …, 2011 - journals.plos.org
Muscle-eye-brain disease (MEB) and Walker Warburg Syndrome (WWS) belong to a
spectrum of autosomal recessive diseases characterized by ocular dysgenesis, neuronal …