Biomaterials with suitable surface modification strategies are contributing significantly to the
rapid development of the field of bone tissue engineering. Despite these encouraging …

Tissue engineering strategies for treating bone loss to date have largely focused on
targeting stem cells or vascularization. Immune cells, including macrophages and T cells …

Bioactive ions released from bioceramics play important roles in bone regeneration;
however, it is unclear how each ionic composition in complex bioceramics exerts its specific …

Calcium phosphate ceramic materials are extensively used for bone replacement and
regeneration in orthopedic, dental, and maxillofacial surgical applications. In order for these …

In the search for more ideal bone graft materials for clinical application, the investigation into
ceramic bone cements or bone void filler is ongoing. Calcium phosphate-based materials …

Electrospun bioactive glass fibers show great potential as scaffolds for bone tissue
engineering due to their architectural biomimicry of the bone extracellular matrix and their …

The functionality or survival of tissue engineering constructs depends on the adequate
vascularization through oxygen transport and metabolic waste removal at the core. This …

Autologous bone grafting remains the gold standard for almost all bone void‐filling
orthopedic surgery. However, autologous bone grafting has several limitations, thus …

Traditional bone replacement materials have been developed with the goal of directing the
osteogenesis of osteoblastic cell lines toward differentiation and therefore achieving …

The success of scaffold‐based bone regeneration approaches strongly depends on the
performance of the biomaterial utilized. Within the efforts of regenerative medicine towards a …