The pulmonary extracellular matrix (ECM) determines the tissue architecture of the lung, and
provides mechanical stability and elastic recoil, which are essential for physiological lung …

Simple Summary Integrins, a superfamily of cell adhesion receptors, were extensively
investigated as therapeutic targets over the last decades, motivated by their multiple …

Biomimetic scaffolds supporting tissue regeneration are complex materials with
multifunctional characteristics. The unique biocompatibility and biodegradability of …

Integrins are large, membrane-spanning, heterodimeric proteins that are essential for a
metazoan existence. All members of the integrin family adopt a shape that resembles a large …

Integrin α5β1 is a major fibronectin receptor critical for cell migration. Upon complex
formation, fibronectin and α5β1 undergo conformational changes. While this is key for cell …

Brown algae (Phaeophyceae) are complex photosynthetic organisms with a very different
evolutionary history to green plants, to which they are only distantly related. These …

Mechanobiology has underpinned many scientific advances in understanding how
biophysical and biomechanical cues regulate cell behavior by identifying mechanosensitive …

Integrins are transmembrane cell–adhesion molecules that carry signals from the outside to
the inside of the cell and vice versa. Like other cell surface receptors, integrins signal in …

Background Cell stiffness is a crucial mechanical property that is closely related to cell
motility. AFM is the most prevalent method used to determine cell stiffness by the quantitative …

Integrins are a large family of molecules that are central regulators in multicellular biology.
They orchestrate cell–cell and cell–extracellular matrix (ECM) adhesive interactions from …