The search for noise-induced cochlear synaptopathy in humans: Mission impossible?

N Bramhall, EF Beach, B Epp, CG Le Prell… - Hearing research, 2019 - Elsevier
Animal studies demonstrate that noise exposure can permanently damage the synapses
between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and …

Hidden hearing loss: a disorder with multiple etiologies and mechanisms

DC Kohrman, G Wan… - Cold Spring …, 2020 - perspectivesinmedicine.cshlp.org
Hidden hearing loss (HHL), a recently described auditory disorder, has been proposed to
affect auditory neural processing and hearing acuity in subjects with normal audiometric …

[图书][B] The sense of hearing

CJ Plack - 2023 - taylorfrancis.com
The Sense of Hearing is a highly accessible introduction to auditory perception, addressing
the fundamental aspects of hearing. This fourth edition has been revised to include up-to …

[HTML][HTML] Impaired speech perception in noise with a normal audiogram: No evidence for cochlear synaptopathy and no relation to lifetime noise exposure

H Guest, KJ Munro, G Prendergast, RE Millman… - Hearing research, 2018 - Elsevier
In rodents, noise exposure can destroy synapses between inner hair cells and auditory
nerve fibers (“cochlear synaptopathy”) without causing hair cell loss. Noise-induced …

Effects of noise exposure on auditory brainstem response and speech-in-noise tasks: A review of the literature

CG Le Prell - International journal of audiology, 2019 - Taylor & Francis
Objective: Short-term noise exposure that induces transient changes in thresholds has
induced permanent cochlear synaptopathy in multiple species. Here, the literature was …

Hearing loss and brain plasticity: the hyperactivity phenomenon

B Herrmann, BE Butler - Brain Structure and Function, 2021 - Springer
Many aging adults experience some form of hearing problems that may arise from auditory
peripheral damage. However, it has been increasingly acknowledged that hearing loss is …

Neural presbyacusis in humans inferred from age-related differences in auditory nerve function and structure

KC Harris, JB Ahlstrom, JW Dias… - Journal of …, 2021 - Soc Neuroscience
A common complaint of older adults is difficulty understanding speech, particularly in
challenging listening conditions. Accumulating evidence suggests that these difficulties may …

Hidden hearing loss impacts the neural representation of speech in background noise

JJM Monaghan, JA Garcia-Lazaro, D McAlpine… - Current Biology, 2020 - cell.com
Many individuals with seemingly normal hearing abilities struggle to understand speech in
noisy backgrounds. To understand why this might be the case, we investigated the neural …

Ecological cocktail party listening reveals the utility of extended high-frequency hearing

BB Monson, J Rock, A Schulz, E Hoffman, E Buss - Hearing Research, 2019 - Elsevier
A fundamental principle of neuroscience is that each species' and individual's sensory
systems are tailored to meet the demands placed upon them by their environments and …

[HTML][HTML] Associations between speech recognition at high levels, the middle ear muscle reflex and noise exposure in individuals with normal audiograms

J Shehorn, O Strelcyk, P Zahorik - Hearing Research, 2020 - Elsevier
It has been hypothesized that noise-induced cochlear synaptopathy in humans may result in
functional deficits such as a weakened middle ear muscle reflex (MEMR) and degraded …