The decisive early phase of bone regeneration

GN Duda, S Geissler, S Checa, S Tsitsilonis… - Nature Reviews …, 2023 - nature.com
Bone has a remarkable endogenous regenerative capacity that enables scarless healing
and restoration of its prior mechanical function, even under challenging conditions such as …

Endometrial stem/progenitor cells: the first 10 years

CE Gargett, KE Schwab… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND The existence of stem/progenitor cells in the endometrium was postulated
many years ago, but the first functional evidence was only published in 2004. The …

The meaning, the sense and the significance: translating the science of mesenchymal stem cells into medicine

P Bianco, X Cao, PS Frenette, JJ Mao, PG Robey… - Nature medicine, 2013 - nature.com
Mesenchymal stem cells (MSCs) are the focus of intensive efforts worldwide directed not
only at elucidating their nature and unique properties but also developing cell-based …

Engineering bioactive scaffolds for skin regeneration

M Hosseini, A Shafiee - Small, 2021 - Wiley Online Library
Large skin wounds pose a major clinical challenge. Scarcity of donor site and postsurgical
scarring contribute to the incomplete or partial loss of function and aesthetic concerns in skin …

The critical role of apoptosis in mesenchymal stromal cell therapeutics and implications in homeostasis and normal tissue repair

C Giacomini, C Granéli, R Hicks, F Dazzi - Cellular & Molecular …, 2023 - nature.com
Mesenchymal stromal cells (MSCs) have been extensively tested for the treatment of
numerous clinical conditions and have demonstrated good safety but mixed efficacy …

MARS: discovering novel cell types across heterogeneous single-cell experiments

M Brbić, M Zitnik, S Wang, AO Pisco, RB Altman… - Nature …, 2020 - nature.com
Although tremendous effort has been put into cell-type annotation, identification of
previously uncharacterized cell types in heterogeneous single-cell RNA-seq data remains a …

Mesenchymal stem or stromal cells: a review of clinical applications and manufacturing practices

RR Sharma, K Pollock, A Hubel, D McKenna - Transfusion, 2014 - Wiley Online Library
Mesenchymal stem cells (MSC s) have recently generated great interest in the fields of
regenerative medicine and immunotherapy due to their unique biologic properties. In this …

Endometrial and menstrual blood mesenchymal stem/stromal cells: biological properties and clinical application

M Bozorgmehr, S Gurung, S Darzi, S Nikoo… - Frontiers in cell and …, 2020 - frontiersin.org
A highly proliferative mesenchymal stem/stromal cell (MSC) population was recently
discovered in the dynamic, cyclically regenerating human endometrium as clonogenic …

Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in …

Q Zhang, S Shi, Y Liu, J Uyanne, Y Shi… - The Journal of …, 2009 - journals.aai.org
Aside from the well-established self-renewal and multipotent differentiation properties,
mesenchymal stem cells exhibit both immunomodulatory and anti-inflammatory roles in …

Concise review: the surface markers and identity of human mesenchymal stem cells

FJ Lv, RS Tuan, KMC Cheung, VYL Leung - Stem cells, 2014 - academic.oup.com
The concept of mesenchymal stem cells (MSCs) is becoming increasingly obscure due to
the recent findings of heterogeneous populations with different levels of stemness within …