Protective Effects of Caesalpinia sappan Linn. and Its Bioactive Compounds on Cardiovascular Organs

MRAA Syamsunarno, R Safitri… - Frontiers in pharmacology, 2021 - frontiersin.org
Cardiovascular diseases are the leading cause of death worldwide. The long-term aim of
cardiovascular disease therapy is to reduce the mortality rate and decelerate the …

Brazilin: An updated literature-based review on its promising therapeutic approaches and toxicological studies

S Jamaddar, C Sarkar, S Akter, MS Mubarak… - South African Journal of …, 2023 - Elsevier
Introduction Brazilin is a promising natural red dye, extracted from the wood of Caesalpinia
sappan L. It exhibits several pharmacological activities including anti-inflammatory …

Brazilin: biological activities and therapeutic potential in chronic degenerative diseases and cancer

DA Nava-Tapia, L Cayetano-Salazar… - Pharmacological …, 2022 - Elsevier
Caesalpinia sappan and Haematoxylum brasiletto belong to the Fabaceae family,
predominantly distributed in Southeast Asia and America. The isoflavonoid brazilin has …

A comprehensive review on chemotaxonomic and phytochemical aspects of homoisoflavonoids, as rare flavonoid derivatives

J Mottaghipisheh, H Stuppner - International Journal of Molecular …, 2021 - mdpi.com
Homoisoflavonoids (3-benzylidene-4-chromanones) are considered as an infrequent
flavonoid class, possessing multi-beneficial bioactivities. The present study gives an …

Antibacterial activity against foodborne pathogens and inhibitory effect on anti-inflammatory mediators' production of Brazilin-enriched extract from Caesalpinia …

T Pattananandecha, S Apichai, J Julsrigival, F Ogata… - Plants, 2022 - mdpi.com
Caesalpinia sappan L. heartwood was collected from Mae Chaem District, Chiang Mai
Province, Thailand. Crude extracts were prepared by Soxhlet's extraction using 50, 60, and …

[HTML][HTML] Bio-actives from Caesalpinia sappan L.: Recent advancements in phytochemistry and pharmacology

MS Rajput, NP Nirmal, SJ Nirmal… - South African Journal of …, 2022 - Elsevier
Caesalpinia sappan L. or Sappanwood is a redwood, full-fledged in numerous parts of
Southeast Asia and well known for its red pigments, dye, food additive, and several …

Brazilin and Caesalpinia sappan L. extract protect epidermal keratinocytes from oxidative stress by inducing the expression of GPX7

HS Hwang, JH Shim - Chinese journal of natural medicines, 2018 - Elsevier
Caesalpinia sappan L., belonging to the family Leguminosae, is a medicinal plant that is
distributed in Southeast Asia. The dried heartwood of this plant is used as a traditional …

In vitro hypoglycemic and antioxidant activities of steamed Polygonatum cyrtonema Hua with various steaming degrees: relationship with homoisoflavonoids

X Nie, L Wang, S Wang, N Yu, Y Lu, W Lyu, X Meng - Food Bioscience, 2023 - Elsevier
Polygonatum cyrtonema Hua, an edible and medicinal plant in China, is usually steamed
and then dried before use. Changes in homoisoflavonoids composition, radical scavenging …

Brazilin treatment produces antidepressant-and anxiolytic-like effects in mice

X Wang, Z Xiu, Y Du, Y Li, J Yang, Y Gao… - Biological and …, 2019 - jstage.jst.go.jp
Increasing evidence shows depression relevant to oxidative stress and inflammation. Anti-
inflammatory strategies or antioxidants have led to the development of new antidepressants …

Naturally occurring homoisoflavonoids: Phytochemistry, biological activities, and synthesis (Part II)

BM Abegaz, HH Kinfe - Natural Product Communications, 2019 - journals.sagepub.com
This review documents all the new homoisoflavonoids (HIFs) that have been reported since
2007, whose total number has grown from 159 in 2007 to 295 at the present time. This …