Objectives The first drug repurposed for the treatment of depression was the tuberculostatic
iproniazid. At present, drugs belonging to new classes of antidepressants still have …

The human gut contains trillions of symbiotic bacteria that play a key role in programming
different aspects of host physiology in health and disease. Psychotropic medications act on …

The therapeutic outcomes in major depressive disorder (MDD), one of the most common
and heterogeneous mental illnesses, are affected by factors that remain unclear and often …

Moving towards a systems psychiatry paradigm embraces the inherent complex interactions
across all levels from micro to macro and necessitates an integrated approach to treatment …

There is increasing interest in the role of the gut microbiota in health and disease. In
particular, gut microbiota influences the Central Nervous System (CNS) development and …

Background: The emergence of multidrug-resistant organisms (MDROs) is a global public
health issue, severely hindering clinicians in administering appropriate antimicrobial …

The human body can be considered a superorganism in which it's eukaryotic cells and
prokaryotic microorganisms coexist. Almost every organ system of the body lives a symbiotic …

According to the WHO, major depressive disorder is the leading cause of disability
worldwide, and it is a major contributor to the overall global burden of disease. The …

Background and objectives: Ketamine and propofol are the general anesthetics that also
have antimicrobial and microbial growth-promoting effects, respectively. Although these …

One of the most fascinating drugs in the anesthesiologist's armament is ketamine, an N-
methyl-D-aspartate receptor antagonist with a myriad of uses. The drug is a dissociative …