PCL-PEG copolymer based injectable thermosensitive hydrogels

MR Dethe, A Prabakaran, H Ahmed, M Agrawal… - Journal of Controlled …, 2022 - Elsevier
A number of stimuli-responsive-based hydrogels has been widely explored in biomedical
applications in the last few decades because of their excellent biodegradability and …

Bispecific antibodies: a mechanistic review of the pipeline

AF Labrijn, ML Janmaat, JM Reichert… - Nature reviews Drug …, 2019 - nature.com
The term bispecific antibody (bsAb) is used to describe a large family of molecules designed
to recognize two different epitopes or antigens. BsAbs come in many formats, ranging from …

Mesenchymal stromal cell homing: mechanisms and strategies for improvement

M Ullah, DD Liu, AS Thakor - Iscience, 2019 - cell.com
Mesenchymal stromal cells (MSCs) have been widely investigated for their therapeutic
potential in regenerative medicine, owing to their ability to home damaged tissue and serve …

Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging

PJ Gawne, F Man, PJ Blower… - Chemical reviews, 2022 - ACS Publications
The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …

Mesenchymal stem cell therapy for the treatment of inflammatory diseases: challenges, opportunities, and future perspectives

S Regmi, S Pathak, JO Kim, CS Yong… - European journal of cell …, 2019 - Elsevier
Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …

Challenges in clinical development of mesenchymal stromal/stem cells: concise review

I Mastrolia, EM Foppiani, A Murgia… - Stem cells …, 2019 - academic.oup.com
Identified 50 years ago, mesenchymal stromal/stem cells (MSCs) immediately generated a
substantial interest among the scientific community because of their differentiation plasticity …

Mesenchymal stem cell-based therapy for cardiovascular disease: progress and challenges

L Bagno, KE Hatzistergos, W Balkan, JM Hare - Molecular Therapy, 2018 - cell.com
Administration of mesenchymal stem cells (MSCs) to diseased hearts improves cardiac
function and reduces scar. These effects occur via stimulation of endogenous repair …

Regenerative abilities of mesenchymal stem cells through mitochondrial transfer

S Paliwal, R Chaudhuri, A Agrawal… - Journal of biomedical …, 2018 - Springer
The past decade has witnessed an upsurge in studies demonstrating mitochondrial transfer
as one of the emerging mechanisms through which mesenchymal stem cells (MSCs) can …

Intra‐articular injection of mesenchymal stem cells for the treatment of osteoarthritis of the knee: a proof‐of‐concept clinical trial

CH Jo, YG Lee, WH Shin, H Kim, JW Chai… - Stem …, 2014 - academic.oup.com
Mesenchymal stem cells (MSCs) are known to have a potential for articular cartilage
regeneration. However, most studies focused on focal cartilage defect through surgical …

Hypoxia inducible factor-1α potentiates jagged 1-mediated angiogenesis by mesenchymal stem cell-derived exosomes

H Gonzalez-King, NA García, I Ontoria-Oviedo… - Stem …, 2017 - academic.oup.com
Insufficient vessel growth associated with ischemia remains an unresolved issue in vascular
medicine. Mesenchymal stem cells (MSCs) have been shown to promote angiogenesis via a …