Many trace metals are essential micronutrients, but also potent toxins. Due to natural and
anthropogenic causes, vastly different trace metal concentrations occur in various habitats …

Abstract The Cation Diffusion Facilitators (CDFs) form a family of membrane-bound proteins
capable of transporting zinc and other heavy metal ions. Involved in metal …

Abstract Initial Cadmium (Cd) isotope fractionation studies in cereals ascribed the retention
of Cd and its light isotopes to the binding of Cd to sulfur (S). To better understand the relation …

Among the biologically required first row, late d-block metals from Mn II to Zn II, the catalytic
and structural reach of Zn II ensures that this essential micronutrient touches nearly every …

Zinc is a redox-inert trace element that is second only to iron in abundance in biological
systems. In cells, zinc is typically buffered and bound to metalloproteins, but it may also exist …

Abstract Plasma membrane Ca2+-ATPases (PMCAs) are key regulators of global Ca2+
homeostasis and local intracellular Ca2+ dynamics. Recently, Neuroplastin (NPTN) and …

P-type ATPases constitute a large ancient super-family of primary active pumps that have
diverse substrate specificities ranging from H+ to phospholipids. The significance of these …

Between 5 and 10% of all proteins of a given organism are estimated to require zinc for
function, and hence zinc is essential for almost any given metabolic process. It is therefore of …

Abstract Phosphorylation-type (P-type) ATPases are ubiquitous primary transporters that
pump cations across cell membranes through the formation and breakdown of a …

Cadmium (Cd) isotopes are an important tool to better understand the inorganic and organic
geochemistry of Cd. Organic ligands play a key role to control the toxicity and mobility of Cd …