Fungal infections are still threatening human health due to resistance to existing drugs, therefore, the design and development of novel antifungal agents is to be necessary and …
V Rao Gollapalli, H Babu Bollikolla… - Chemistry & …, 2023 - Wiley Online Library
Our current work is aimed at synthesizing novel substituted 1, 2, 4‐triazolyl‐fluoroquinolone analogs and study of their biological activity to find active promising molecules. The …
Tuberculosis is a highly infectious disease and it is a global threat in particular affecting people from developing countries. It is thought that nearly one-third of the global population …
KA Ajin, S Arun Kumar, M Singh… - Chemistry & …, 2023 - Wiley Online Library
Mycobacterium tuberculosis (Mtb) has numerous cell wall and non‐cell wall mediated receptors for drug action, of which cell wall mediated targets were found to be more …
N Myakala, V Thumma, K Kandula, N Rayala… - Molecular Diversity, 2024 - Springer
Two novel series of quinazolinone based isoxazole and isoxazoline hybrid compounds were synthesized from 6-aminoquinazolinone as a key precursor. The title compounds were …
H Verma, D Pathak, U Singh - Int. J. Pharm. Sci. Drug Res, 2023 - researchgate.net
A new series of 5-(chloromethyl)-3-(substituted phenyl) isoxazole was synthesized in the presence of sodium hydroxide, substituted aromatic aldehyde (1) combine to produce oxime …
T Chitre, S Jadhav, K Asgaonkar… - Current Indian …, 2023 - benthamdirect.com
Background Tuberculosis (TB) is caused by Mycobacterium tuberculosis and is one of the most contagious and fatal human pathogens which necessitates the development of …