Brain aging mechanisms with mechanical manifestations
Y Blinkouskaya, A Caçoilo, T Gollamudi… - Mechanisms of ageing …, 2021 - Elsevier
Brain aging is a complex process that affects everything from the subcellular to the organ
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …
The human connectome project's neuroimaging approach
Noninvasive human neuroimaging has yielded many discoveries about the brain. Numerous
methodological advances have also occurred, though inertia has slowed their adoption. This …
methodological advances have also occurred, though inertia has slowed their adoption. This …
Amyloid and tau PET-positive cognitively unimpaired individuals are at high risk for future cognitive decline
A major unanswered question in the dementia field is whether cognitively unimpaired
individuals who harbor both Alzheimer's disease neuropathological hallmarks (that is …
individuals who harbor both Alzheimer's disease neuropathological hallmarks (that is …
Heterogeneous aging across multiple organ systems and prediction of chronic disease and mortality
Biological aging of human organ systems reflects the interplay of age, chronic disease,
lifestyle and genetic risk. Using longitudinal brain imaging and physiological phenotypes …
lifestyle and genetic risk. Using longitudinal brain imaging and physiological phenotypes …
APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline
Vascular contributions to dementia and Alzheimer's disease are increasingly recognized,,,,–.
Recent studies have suggested that breakdown of the blood–brain barrier (BBB) is an early …
Recent studies have suggested that breakdown of the blood–brain barrier (BBB) is an early …
First-in-human prediction of chronic pain state using intracranial neural biomarkers
Chronic pain syndromes are often refractory to treatment and cause substantial suffering
and disability. Pain severity is often measured through subjective report, while objective …
and disability. Pain severity is often measured through subjective report, while objective …
Genetic variants associated with longitudinal changes in brain structure across the lifespan
Human brain structure changes throughout the lifespan. Altered brain growth or rates of
decline are implicated in a vast range of psychiatric, developmental and neurodegenerative …
decline are implicated in a vast range of psychiatric, developmental and neurodegenerative …
[HTML][HTML] Shared and unique brain network features predict cognitive, personality, and mental health scores in the ABCD study
How individual differences in brain network organization track behavioral variability is a
fundamental question in systems neuroscience. Recent work suggests that resting-state and …
fundamental question in systems neuroscience. Recent work suggests that resting-state and …
[HTML][HTML] SynthStrip: skull-stripping for any brain image
The removal of non-brain signal from magnetic resonance imaging (MRI) data, known as
skull-stripping, is an integral component of many neuroimage analysis streams. Despite their …
skull-stripping, is an integral component of many neuroimage analysis streams. Despite their …
Accuracy of tau positron emission tomography as a prognostic marker in preclinical and prodromal Alzheimer disease: a head-to-head comparison against amyloid …
Importance Tau positron emission tomography (PET) tracers have proven useful for the
differential diagnosis of dementia, but their utility for predicting cognitive change is unclear …
differential diagnosis of dementia, but their utility for predicting cognitive change is unclear …