Double-membrane vesicles as platforms for viral replication

G Wolff, CE Melia, EJ Snijder, M Bárcena - Trends in microbiology, 2020 - cell.com
Viruses, as obligate intracellular parasites, exploit cellular pathways and resources in a
variety of fascinating ways. A striking example of this is the remodelling of intracellular …

Rewiring cellular networks by members of the Flaviviridae family

CJ Neufeldt, M Cortese, EG Acosta… - Nature Reviews …, 2018 - nature.com
Members of the Flaviviridae virus family comprise a large group of enveloped viruses with a
single-strand RNA genome of positive polarity. Several genera belong to this family …

Autophagy and inflammation

Y Matsuzawa-Ishimoto, S Hwang… - Annual review of …, 2018 - annualreviews.org
The cellular degradative pathway of autophagy has a fundamental role in immunity. Here,
we review the function of autophagy and autophagy proteins in inflammation. We discuss …

Contribution of autophagy machinery factors to HCV and SARS-CoV-2 replication organelle formation

WI Twu, JY Lee, H Kim, V Prasad, B Cerikan… - Cell reports, 2021 - cell.com
Positive-strand RNA viruses replicate in close association with rearranged intracellular
membranes. For hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus …

Inhibition of ATG12-mediated autophagy by miR-214 enhances radiosensitivity in colorectal cancer

JL Hu, GY He, XL Lan, ZC Zeng, J Guan, Y Ding… - Oncogenesis, 2018 - nature.com
Radioresistance hampers success in the treatment of patients with advanced colorectal
cancer (CRC). Improving our understanding of the underlying mechanisms of …

Hepatitis C virus-induced autophagy and host innate immune response

ST Chan, JJ Ou - Viruses, 2017 - mdpi.com
Autophagy is a catabolic process that is important for maintaining cellular homeostasis. This
pathway in hepatocytes is stimulated and controlled by the hepatitis C virus (HCV)—upon …

Manipulation of autophagy by (+) RNA viruses

HH Wong, S Sanyal - Seminars in cell & developmental biology, 2020 - Elsevier
Autophagy is an evolutionarily conserved process central to host metabolism. Among its
major functions are conservation of energy during starvation, recycling organelles, and …

[HTML][HTML] Secretion of hepatitis C virus replication intermediates reduces activation of toll-like receptor 3 in hepatocytes

O Grünvogel, O Colasanti, JY Lee, V Klöss… - Gastroenterology, 2018 - Elsevier
Background & Aims Hepatitis C virus (HCV) infections most often result in chronic outcomes,
although the virus constantly produces replication intermediates, in particular double …

Long noncoding RNA HAGLROS promotes cell proliferation, inhibits apoptosis and enhances autophagy via regulating miR-5095/ATG12 axis in hepatocellular …

H Wei, J Hu, J Pu, Q Tang, W Li, R Ma, Z Xu… - International …, 2019 - Elsevier
In this research, we planned to dig the possible influences and mechanism of long
noncoding (lnc) RNA HAGLROS in the development and progression of hepatocellular …

Hepatitis B virus subverts the autophagy elongation complex Atg5-12/16L1 and does not require Atg8/LC3 lipidation for viral maturation

T Döring, L Zeyen, C Bartusch, R Prange - Journal of virology, 2018 - Am Soc Microbiol
Previous studies indicated that hepatitis B virus (HBV) stimulates autophagy to favor its
production. To understand how HBV co-opts autophagy as a proviral machinery, we studied …