Understanding and preventing the global increase of inflammatory bowel disease

GG Kaplan, SC Ng - Gastroenterology, 2017 - Elsevier
The inflammatory bowel diseases (IBDs) are contemporary conditions of industrialized
societies. The prevalence of IBD continues to increase steadily in Western countries, and …

Intestinal microbiota, fecal microbiota transplantation, and inflammatory bowel disease

AR Weingarden, BP Vaughn - Gut microbes, 2017 - Taylor & Francis
Inflammatory bowel disease (IBD) is a complex set of diseases that lead to chronic
inflammation in the gastrointestinal tract. Although the etiology of IBD is not fully understood …

Parabacteroides distasonis alleviates obesity and metabolic dysfunctions via production of succinate and secondary bile acids

K Wang, M Liao, N Zhou, L Bao, K Ma, Z Zheng… - Cell reports, 2019 - cell.com
We demonstrated the metabolic benefits of Parabacteroides distasonis (PD) on decreasing
weight gain, hyperglycemia, and hepatic steatosis in ob/ob and high-fat diet (HFD)-fed mice …

Gut microbial profile is altered in primary biliary cholangitis and partially restored after UDCA therapy

R Tang, Y Wei, Y Li, W Chen, H Chen, Q Wang, F Yang… - Gut, 2018 - gut.bmj.com
Objective A close relationship between gut microbiota and some chronic liver disorders has
recently been described. Herein, we systematically performed a comparative analysis of the …

Alterations of gut microbiome in autoimmune hepatitis

Y Wei, Y Li, LI Yan, C Sun, Q Miao, Q Wang, X Xiao… - Gut, 2020 - gut.bmj.com
Objective The significance of the liver-microbiome axis has been increasingly recognised as
a major modulator of autoimmunity. The aim of this study was to take advantage of a large …

The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls

M Kummen, K Holm, JA Anmarkrud, S Nygård… - Gut, 2017 - gut.bmj.com
Objective Gut microbiota could influence gut, as well as hepatic and biliary immune
responses. We therefore thoroughly characterised the gut microbiota in primary sclerosing …

Gut dysbiosis induces the development of pre-eclampsia through bacterial translocation

X Chen, P Li, M Liu, H Zheng, Y He, MX Chen, W Tang… - Gut, 2020 - gut.bmj.com
Objective Pre-eclampsia (PE) is one of the malignant metabolic diseases that complicate
pregnancy. Gut dysbiosis has been identified for causing metabolic diseases, but the role of …

Pglyrp-Regulated Gut Microflora Prevotella falsenii, Parabacteroides distasonis and Bacteroides eggerthii Enhance and Alistipes finegoldii Attenuates Colitis in …

R Dziarski, SY Park, DR Kashyap, SE Dowd, D Gupta - PloS one, 2016 - journals.plos.org
Dysbiosis is a hallmark of inflammatory bowel disease (IBD), but it is unclear which specific
intestinal bacteria predispose to and which protect from IBD and how they are regulated …

The association between the gut microbiota and the inflammatory bowel disease activity: a systematic review and meta-analysis

M Prosberg, F Bendtsen, I Vind… - Scandinavian journal …, 2016 - Taylor & Francis
Background: The pathogenesis of inflammatory bowel diseases (IBD) involves complex
interactions between the microbiome and the immune system. We evaluated the association …

Mediterranean diet to prevent the development of colon diseases: a meta-analysis of gut microbiota studies

O Illescas, M Rodríguez-Sosa, M Gariboldi - Nutrients, 2021 - mdpi.com
Gut microbiota dysbiosis is a common feature in colorectal cancer (CRC) and inflammatory
bowel diseases (IBD). Adoption of the Mediterranean diet (MD) has been proposed as a …