[HTML][HTML] Ebola virus disease

ST Jacob, I Crozier, WA Fischer, A Hewlett… - Nature reviews Disease …, 2020 - nature.com
Ebola virus disease (EVD) is a severe and frequently lethal disease caused by Ebola virus
(EBOV). EVD outbreaks typically start from a single case of probable zoonotic transmission …

[HTML][HTML] Ebola virus disease: An emerging and re-emerging viral threat

M Rojas, DM Monsalve, Y Pacheco… - Journal of …, 2020 - Elsevier
The genus Ebolavirus from the family Filoviridae is composed of five species including
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …

A forgotten episode of Marburg virus disease: Belgrade, Yugoslavia, 1967

ES Ristanović, NS Kokoškov, I Crozier… - Microbiology and …, 2020 - Am Soc Microbiol
In 1967, several workers involved in poliomyelitis vaccine development and production fell
ill at three different locations in Europe with a severe and often lethal novel disease …

Filovirus disease outbreaks: a chronological overview

S Languon, O Quaye - Virology: research and treatment, 2019 - journals.sagepub.com
Filoviruses cause outbreaks which lead to high fatality in humans and non-human primates,
thus tagging them as major threats to public health and species conservation. In this review …

[HTML][HTML] Marburg virus pathogenesis–differences and similarities in humans and animal models

K Shifflett, A Marzi - Virology journal, 2019 - Springer
Marburg virus (MARV) is a highly pathogenic virus associated with severe disease and
mortality rates as high as 90%. Outbreaks of MARV are sporadic, deadly, and often …

[HTML][HTML] Recent successes in therapeutics for Ebola virus disease: no time for complacency

PL Iversen, CD Kane, X Zeng, RG Panchal… - The Lancet Infectious …, 2020 - thelancet.com
The PALM trial in the Democratic Republic of the Congo identified a statistically significant
survival benefit for two monoclonal antibody-based therapeutics in the treatment of acute …

Ebola virus disease: epidemiology, clinical features, management, and prevention

E Nicastri, G Kobinger, F Vairo, C Montaldo… - Infectious Disease …, 2019 - id.theclinics.com
Ebola virus disease (EVD), also known as Ebola hemorrhagic fever or Ebola, is caused by
the Ebola virus (EBOV). EBOV is a linear, nonsegmented, single negative-stranded RNA …

[PDF][PDF] Structure-based design of prefusion-stabilized filovirus glycoprotein trimers

L Rutten, MSA Gilman, S Blokland, J Juraszek… - Cell reports, 2020 - cell.com
Ebola virus causes severe hemorrhagic fever, often leading to death in humans. The trimeric
fusion glycoprotein (GP) is the sole target for neutralizing antibodies and is the major focus …

[HTML][HTML] Marburg virus disease: the paradox of Nigeria's preparedness and priority effects in co-epidemics

RC Reuben, SA Abunike - Bulletin of the National Research Centre, 2023 - Springer
Background The recent outbreaks of Marburg virus disease (MVD) in Guinea and Ghana
have become a major public health concern not only to the West African sub-region but a …

[HTML][HTML] Diagnostics of Ebola virus

A Bettini, D Lapa, AR Garbuglia - Frontiers in Public Health, 2023 - frontiersin.org
Ebola is a highly pathogenic virus, which in humans reaches a mortality rate above 50%.
Due to a lack of laboratories in territories where Ebola viruses are endemic and the limited …