Hearing and dementia: from ears to brain

JCS Johnson, CR Marshall, RS Weil, DE Bamiou… - Brain, 2021 - academic.oup.com
The association between hearing impairment and dementia has emerged as a major public
health challenge, with significant opportunities for earlier diagnosis, treatment and …

Hearing loss and cognition: what we know and where we need to go

DS Powell, ES Oh, NS Reed, FR Lin… - Frontiers in aging …, 2022 - frontiersin.org
Although a causal association remains to be determined, epidemiologic evidence suggests
an association between hearing loss and increased risk of dementia. If we determine the …

Hearing impairment is associated with cognitive decline, brain atrophy and tau pathology

HF Wang, W Zhang, ET Rolls, Y Li, L Wang, YH Ma… - …, 2022 - thelancet.com
Background Hearing impairment was recently identified as the most prominent risk factor for
dementia. However, the mechanisms underlying the link between hearing impairment and …

Hearing impairment and cognition in an aging world

DS Powell, ES Oh, FR Lin, JA Deal - … of the Association for Research in …, 2021 - Springer
With the increasing number of older adults around the world, the overall number of dementia
cases is expected to rise dramatically in the next 40 years. In 2020, nearly 6 million …

Novel insights into RIPK1 as a promising target for future Alzheimer's disease treatment

S Li, L Qu, X Wang, L Kong - Pharmacology & Therapeutics, 2022 - Elsevier
Alzheimer's disease (AD) is an intractable neurodegenerative disease showing a clinical
manifestation with memory loss, cognitive impairment and behavioral dysfunction. The …

GDF1 ameliorates cognitive impairment induced by hearing loss

L Pan, C Li, L Meng, G Zhang, L Zou, Y Tian, S Chen… - Nature Aging, 2024 - nature.com
Hearing loss is associated with an increased risk of Alzheimer disease (AD). However, the
mechanisms of hearing loss promoting the onset of AD are poorly understood. Here we …

Longitudinal changes in hearing and visual impairments and risk of dementia in older adults in the United States

PH Hwang, WT Longstreth, SM Thielke… - JAMA network …, 2022 - jamanetwork.com
Importance Hearing and vision problems are individually associated with increased
dementia risk, but the impact of having concurrent hearing and vision deficits, ie, dual …

Longitudinal associations of subclinical hearing loss with cognitive decline

AL Irace, NM Armstrong, JA Deal… - The Journals of …, 2022 - academic.oup.com
Background Several studies have demonstrated that age-related hearing loss is associated
with cognitive decline. We investigated whether subclinical hearing loss (SCHL) or imperfect …

Current Alzheimer disease research highlights: evidence for novel risk factors

WD Brenowitz, Y Xiang, CT McEvoy, C Yang… - Chinese medical …, 2021 - mednexus.org
Alzheimer disease (AD) is the most common type of dementia characterized by the
progressive cognitive and social decline. Clinical drug targets have heavily focused on the …

Methods to address self-selection and reverse causation in studies of neighborhood environments and brain health

LM Besser, WD Brenowitz, OL Meyer… - International journal of …, 2021 - mdpi.com
Preliminary evidence suggests that neighborhood environments, such as socioeconomic
disadvantage, pedestrian and physical activity infrastructure, and availability of …