Introduction Diabetic retinopathy, a significant trigger for blindness among working age individuals with diabetes, poses a substantial global health challenge. Understanding its …
L Pelusi, J Hurst, N Detta, C Pipino… - Frontiers in …, 2024 - frontiersin.org
Introduction Diabetic retinopathy (DR) is a microvascular complication of diabetes in which neurodegeneration has been recently identified as a driving force. In the last years …
EMV Oosten, AD ávan der Meer - Lab on a Chip, 2025 - pubs.rsc.org
The retina is a complex and highly metabolic tissue in the back of the eye essential for human vision. Retinal diseases can lead to loss of vision in early and late stages of life …
Background Tocotrienol is a vitamin E analogue that is known to exert anti-inflammatory and antioxidant effects. Hence, in the current study, the effects of TRF on the expression of pro …
D Yuan, Y Xu, L Xue, W Zhang, L Gu, Q Liu - Heliyon, 2024 - cell.com
Objective Oxidative stress-induced retinal neurodegenerative changes are among the pathological alterations observed in diabetic retinopathy. Resveratrol (RSV), a polyphenolic …
V Klochkov, CM Chan, WW Lin - Biomedicines, 2024 - pmc.ncbi.nlm.nih.gov
Background: Diabetic retinopathy is the most common retinal vascular disease, affecting the retina's blood vessels and causing chronic inflammation, oxidative stress, and, ultimately …
Astrocytes are the principle glial cells of the central nervous system and play an active role in maintaining proper metabolism in surrounding neurons. Because of their involvement in …
AIM To investigate the stability of the seven housekeeping genes: beta-actin (ActB), glyceraldehyde-3-phosphate dehydrogenase (GAPDH), 18s ribosomal unit 5 (18s) …
Y Zhao, Y Chen, N Yan - Biomedicines, 2024 - mdpi.com
Diabetic retinopathy (DR) is one of the most severe complications of diabetes mellitus and potentially leads to significant visual impairment and blindness. The complex mechanisms …