Emerging roles of keratinocytes in nociceptive transduction and regulation

X Xu, C Yu, L Xu, J Xu - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Keratinocytes are the predominant block-building cells in the epidermis. Emerging evidence
has elucidated the roles of keratinocytes in a wide range of pathophysiological processes …

Cutaneous targets for topical pain medications in patients with neuropathic pain: individual differential expression of biomarkers supports the need for personalized …

PJ Albrecht, Y Liu, G Houk, B Ruggiero, D Banov… - Pain …, 2024 - journals.lww.com
Objectives: The study intended to identify objective biomarkers in PHN skin on a patient-by-
patient personalized medicine platform. The totality of biopsy biomarker data can provide a …

ELFN1 is a new extracellular matrix (ECM)-associated protein

S Ayhan, A Dursun - Life Sciences, 2024 - Elsevier
Aims The ELFN1, discovered in 2007, is a single-pass transmembrane protein. Studies
conducted thus far to elucidate the function of the Elfn1 have been limited only to animal …

Keratinocyte biomarkers distinguish painful diabetic peripheral neuropathy patients and correlate with topical lidocaine responsiveness

PJ Albrecht, G Houk, E Ruggiero, M Dockum… - Frontiers in Pain …, 2021 - frontiersin.org
This study investigated quantifiable measures of cutaneous innervation and algesic
keratinocyte biomarkers to determine correlations with clinical measures of patient pain …

Intradermal miR-16–5p targets Akt3 and reduces RTX-induced postherpetic neuralgia-mimic pain in mice

D Zhang, L Ma, X Tan, W Deng, S Wen, Y Li… - European Journal of …, 2023 - Elsevier
The molecular mechanisms of refractory pain in postherpetic neuralgia (PHN) patients are
not fully understood. PHN may be related to skin abnormality after herpes zoster induced …

Neurological Aspects of Delusional Infestation

AL Oaklander - The Physician's Guide to Delusional Infestation, 2024 - Springer
Neuropathic itch is a type of itch caused by illness and malfunctioning of the same types of
neurons in the central and peripheral nervous system that can cause neuropathic pain …

[PDF][PDF] Neuromodulatory Effect of Kappa Opioid Receptor Activation on Spinal Network Activity

PN Ozogbuda - 2018 - prism.ucalgary.ca
Dynorphin is a potent anti-nociceptive neuropeptide ubiquitously expressed throughout the
peripheral and central nervous system. Previous studies have shown that dynorphin is co …