The kynurenine pathway as a novel link between allergy and the gut microbiome

AP Van der Leek, Y Yanishevsky… - Frontiers in …, 2017 - frontiersin.org
In the past few decades, the indoleamine 2, 3 dioxygenase (IDO) subset of the kynurenine
(KYN) pathway of tryptophan (TRP) metabolism has been the subject of much research in …

Membrane microdomain disassembly inhibits MRSA antibiotic resistance

E García-Fernández, G Koch, RM Wagner, A Fekete… - Cell, 2017 - cell.com
A number of bacterial cell processes are confined functional membrane microdomains
(FMMs), structurally and functionally similar to lipid rafts of eukaryotic cells. How bacteria …

Three-dimensional chiral morphodynamics of chemomechanical active shells

S Yin, B Li, XQ Feng - … of the National Academy of Sciences, 2022 - National Acad Sciences
Morphogenesis of active shells such as cells is a fundamental chemomechanical process
that often exhibits three-dimensional (3D) large deformations and chemical pattern …

The cell envelope of Staphylococcus aureus selectively controls the sorting of virulence factors

X Zheng, G Marsman, KA Lacey, JR Chapman… - Nature …, 2021 - nature.com
Staphylococcus aureus bi-component pore-forming leukocidins are secreted toxins that
directly target and lyse immune cells. Intriguingly, one of the leukocidins, Leukocidin AB …

Nigella sativa essential oil and its bioactive compounds as resistance modifiers against Staphylococcus aureus

A Mouwakeh, A Kincses, M Nové… - Phytotherapy …, 2019 - Wiley Online Library
Nigella sativa essential oil (EO) and its compounds (thymoquinone, carvacrol, and p‐
cymene) have a broad antimicrobial spectrum. The aim of this study was to investigate the …

Polyhedral liquid droplets: Recent advances in elucidation and application

O Marin, M Tkachev, E Sloutskin, M Deutsch - Current opinion in colloid & …, 2020 - Elsevier
The rediscovery of temperature-controlled self-faceting, shaping, and splitting transitions in
liquid oil-in-water emulsion droplets, has recently led to a significant progress in the …

Flotillin-mediated stabilization of unfolded proteins in bacterial membrane microdomains

M Ukleja, L Kricks, G Torrens, I Peschiera… - Nature …, 2024 - nature.com
The function of many bacterial processes depends on the formation of functional membrane
microdomains (FMMs), which resemble the lipid rafts of eukaryotic cells. However, the …

Organization of peptidoglycan synthesis in nodes and separate rings at different stages of cell division of Streptococcus pneumoniae

AJ Perez, MJ Boersma, KE Bruce… - Molecular …, 2021 - Wiley Online Library
Bacterial peptidoglycan (PG) synthesis requires strict spatiotemporal organization to
reproduce specific cell shapes. In ovoid‐shaped Streptococcus pneumoniae (Spn), septal …

Penicillin-binding protein 1 (PBP1) of Staphylococcus aureus has multiple essential functions in cell division

K Wacnik, VA Rao, X Chen, L Lafage, M Pazos… - MBio, 2022 - Am Soc Microbiol
Bacterial cell division is a complex process requiring the coordination of multiple
components to allow the appropriate spatial and temporal control of septum formation and …

Topology-driven surface patterning of liquid spheres

S Das, AV Butenko, Y Mastai, M Deutsch, E Sloutskin - Nature Physics, 2022 - nature.com
Surfaces of classical spherical liquid droplets are isotropic, promoting the random
distribution of surface-adsorbed molecules. Here we demonstrate a counterintuitive …