Serpins are a superfamily of proteins, whose membership is based on the presence of a
single common core domain consisting of three β-sheets and 8-9 R-helices, and with a set of …

The serpins (serine proteinase inhibitors) are a superfamily of proteins (350–500 amino
acids in size) that fold into a conserved structure and employ a unique suicide substrate-like …

Serpins are a broadly distributed family of protease inhibitors that use a conformational
change to inhibit target enzymes. They are central in controlling many important proteolytic …

Abiotic stress conditions adversely affect plant growth, resulting in significant decline in crop
productivity. To mitigate and recover from the damaging effects of such adverse …

The serine protease inhibitors (SPIs) are widely distributed in living organisms like bacteria,
fungi, plants, and humans. The main function of SPIs as protease enzymes is to regulate the …

Recent studies have revealed the operation of a long-distance communication network
operating within the vascular system of higher plants. The evolutionary development of this …

Proteases, though essentially indispensable to the maintenance and survival of their host
organisms, can be potentially damaging when overexpressed or present in higher …

Highlights•The human proteasome is the second largest drug target class.•Few prototypic
proteases are standard tools for the discovery of novel inhibitors.•Peptide protease inhibitors …

The evolution of intercellular communication had an important role in the increasing
complexity of both multicellular and supracellular organisms. Plasmodesmata, the …

Plants are known to have many secondary metabolites and phytochemical compounds
which are highly explored at biochemical and molecular genetics level and exploited …