Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Extracellular vesicles (EVs) are small membrane‐bound vesicles released by cells under
various conditions. They are found in the extracellular milieu in all biological fluids. As the …

Objective: The lymphatic system is a circulatory system that unidirectionally drains the
interstitial tissue fluid back to blood circulation. Although lymph is utilized by leukocytes for …

Rheumatoid arthritis (RA) is a heterogeneous autoimmune disorder that leads to severe joint
deformities, negatively affecting the patient's quality of life. Extracellular vesicles (EVs) …

Although much has been made of the role of HMGB1 acting as an acute damage associated
molecular pattern (DAMP) molecule, prompting the response to tissue damage or injury, it is …

Patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) demonstrate
increased circulating microparticles (MP). These vesicles, primarily those that form immune …

Background Endothelial activation and damage is commonly observed in patients with
systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) and is related to …

Cells can communicate with each other through extracellular vesicles (EVs), which are
membrane-bound structures that transport proteins, lipids and nucleic acids. These …

COPD is a major cause of morbidity and mortality worldwide. Multimorbidity is common in
COPD patients and a key modifiable factor, which requires timely identification and targeted …

Extracellular vesicles (EVs) isolated from plasma are increasingly recognized as promising
circulating biomarkers for disease discovery and progression, as well as for therapeutic drug …