The RET proto-oncogene has been well-studied. RET is involved in many different
physiological and developmental functions. When altered, RET mutations influence disease …

The rearranged during transfection (RET) proto-oncogene was identified in 1985 and, very
soon thereafter, a rearrangement named RET/PTC was discovered in papillary thyroid …

Thyroid cancer is a common type of endocrine malignancy, and its incidence has been
steadily increasing in many regions of the world. Initiation and progression of thyroid cancer …

Nuclear architecture—the spatial arrangement of chromosomes and other nuclear
components—provides a framework for organizing and regulating the diverse functional …

Thyroid cancer is one of the few malignancies that are increasing in incidence. Recent
advances have improved our understanding of its pathogenesis; these include the …

Materials and Methods The study cohort was retrieved by a retrospective computerized
search of all thyroid FNA performed at the University of Pennsylvania Medical Center …

Papillary carcinoma is the most common type of thyroid malignancy. It has been recently
shown that these tumors commonly have one of three genetic alterations: BRAF point …

The variety of diseases caused by mutations in RET receptor tyrosine kinase provides a
classic example of phenotypic heterogeneity. Gain-of-function mutations of RET are …

Rearrangement of the RET gene, also known as RET/PTC rearrangement, is the most
common genetic alteration identified to date in thyroid papillary carcinomas. The prevalence …

The authors review anatomical, clinical characteristics and prevalence of thyroid
microcarcinoma. Diagnostic procedures and risk factors of aggressiveness at diagnosis and …