Advanced stages of cancer are highly associated with short overall survival in patients due
to the lack of long-term treatment options following the standard form of care. New options …

Cells require tight regulation of the intracellular redox balance and consequently of reactive
oxygen species for proper redox signaling and maintenance of metal (eg, of iron and …

Auranofin is an oral gold (I) compound, initially developed for the treatment of rheumatoid
arthritis. Currently, Auranofin is under investigation for oncological application within a drug …

Gold (I) complexes such as auranofin have been used for decades to treat symptoms of
rheumatoid arthritis and have also demonstrated a considerable potential as new anticancer …

Gold (III) complexes have emerged as a versatile and effective class of metal‐based
anticancer agents. The development of various types of ligands capable of stabilizing the …

Gold-based anticancer agents have gained the widespread attention of medicinal inorganic
chemists due to their unique chemical properties and strong antiproliferative potency …

Electrospray ionization mass spectrometry (ESI MS) is a powerful investigative tool to
analyze the reactions of metallodrugs with proteins and peptides and characterize the …

Following recent work on heterometallic titanocene–gold complexes as potential
chemotherapeutics for renal cancer, we report here on the synthesis, characterization and …

Gold compounds form a new class of promising anticancer agents with innovative modes of
action. It is generally believed that anticancer gold compounds, at variance with clinically …

The organometallic AuI bis‐N‐heterocyclic carbene complex [Au (9‐methylcaffeine‐8‐
ylidene) 2]+(AuTMX2) was previously shown to selectively and potently stabilise telomeric …