Anti-amnestic effect of curcumin in combination with donepezil, an anticholinesterase drug: involvement of cholinergic system

AJ Akinyemi, G Oboh, SI Oyeleye, O Ogunsuyi - Neurotoxicity research, 2017 - Springer
Recently, combination therapy involving cholinesterase (ChE) inhibitor with other
neuroprotective agents has shown better desirable effect in the management/prevention of …

Curcumin administration mitigates cyclophosphamide-induced oxidative damage and restores alteration of enzymes associated with cognitive function in rats' brain

SF Akomolafe, TA Olasehinde, SI Oyeleye… - Neurotoxicity …, 2020 - Springer
The use of chemotherapeutic drugs is associated with oxidative damage, cognitive
dysfunction, and brain damage. This study sought to investigate the neuroprotective effect of …

Of mice and men on MDMA: A translational comparison of the neuropsychobiological effects of 3, 4-methylenedioxymethamphetamine ('Ecstasy')

MA Aguilar, MP García-Pardo, AC Parrott - Brain research, 2020 - Elsevier
Abstract MDMA (3, 4-methylendioxymethamphetamine), also known as Ecstasy, is a
stimulant drug recreationally used by young adults usually in dance clubs and raves. Acute …

Beetroot supplemented diet exhibit anti-amnesic effect via modulation of cholinesterases, purinergic enzymes, monoamine oxidase and attenuation of redox …

TA Olasehinde, SI Oyeleye, CU Ibeji… - Nutritional …, 2022 - Taylor & Francis
Objectives Beta vulgaris, commonly known as beetroot, is a vegetable that contains red
pigment and rich in betalains, phenolic acids, and flavonoids. This study was designed to …

Molecular, histological and behavioral evidences for neuroprotective effects of minocycline against nicotine-induced neurodegeneration and cognition impairment …

M Motaghinejad, N Farokhi, M Motevalian… - Behavioural Brain …, 2020 - Elsevier
Aim Neurodegeneration is one of the serious adverse effects of stimulant agents such as
nicotine. Minocycline possess established neuroprotective properties. The role of CREB …

[HTML][HTML] Aqueous extracts of two tropical ethnobotanicals (Tetrapleura tetraptera and Quassia undulata) improved spatial and non-spatial working memories in …

VO Odubanjo, EO Ibukun, G Oboh… - Biomedicine & …, 2018 - Elsevier
Background: Tetrapleura tetraptera (TT) and Quassia undulata (QU) are two predominant
tropical ethnobotanicals with various medicinal values but are commonly used in folklore for …

The modulatory effects of alkaloid extracts of Cannabis sativa, Datura stramonium, Nicotiana tabacum and male Carica papaya on neurotransmitter, neurotrophic …

OW Fasakin, G Oboh, AO Ademosun, AO Lawal - Inflammopharmacology, 2022 - Springer
This study investigated the modulatory effects of alkaloid extracts of Cannabis sativa
(CSAE), Datura stramonium (DSAE), Nicotiana tabacum (NTAE) and male Carica papaya …

Modulatory effects of Cannabis sativa co-administration with tramadol and codeine on cognitive function in male rats

AO Ademosun, OF Ajeigbe, BO Lawrence, G Oboh - NeuroToxicology, 2023 - Elsevier
Most teenagers mix up various psychoactive cocktail substances in combinations to get
intoxicated. The role of the mixture combination of codeine (CDE), tramadol (TMD), and …

Curcumin improves episodic memory in cadmium induced memory impairment through inhibition of acetylcholinesterase and adenosine deaminase activities in a rat …

AJ Akinyemi, PK Okonkwo, OA Faboya… - Metabolic brain …, 2017 - Springer
Curcumin, the main polyphenolic component of turmeric (Curcuma longa) rhizomes has
been reported to exert cognitive enhancing potential with limited scientific basis. Hence, this …

[HTML][HTML] Tiger nut/coconut dietary intervention as antidotal nutritional remediation strategy against neurobehavioural deficits following organophosphate-induced gut …

LA Enye, EE Edem, LI Onyeogaziri, A Yusuf… - Toxicology Reports, 2024 - Elsevier
Organophosphate poisoning remains a global health crisis without efficacious treatments to
prevent neurotoxicity. We examined whether antidotal tiger nut and coconut dietary …