Integrated immunologic monitoring in solid organ transplantation: the road toward torque Teno virus-guided immunosuppression

P Jaksch, I Görzer, E Puchhammer-Stöckl… - Transplantation, 2022 - journals.lww.com
Potent immunosuppressive drugs have been introduced into clinical care for solid organ
transplant recipients. It is now time to guide these drugs on an individual level to optimize …

Understanding torquetenovirus (TTV) as an immune marker

EJ Gore, L Gard, HGM Niesters… - Frontiers in …, 2023 - frontiersin.org
Torquetenovirus (TTV), a small, single stranded anellovirus, is currently being explored as a
marker of immunocompetence in patients with immunological impairment and inflammatory …

Application of artificial intelligence in precision marketing

X Yang, H Li, L Ni, T Li - Journal of Organizational and End User …, 2021 - igi-global.com
The development of artificial intelligence technology has greatly helped social productivity
and economic growth. At the same time, we have changed modern marketing methods …

A multicentre, patient-and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided …

F Haupenthal, J Rahn, F Maggi, F Gelas, P Bourgeois… - Trials, 2023 - Springer
Background Immunosuppression after kidney transplantation is mainly guided via plasma
tacrolimus trough level, which cannot sufficiently predict allograft rejection and infection. The …

Torque teno virus viral load predicts SARS‐CoV‐2 vaccine response in kidney transplant recipients

M Solis, I Benotmane, F Gallais… - Journal of Medical …, 2023 - Wiley Online Library
Transplant recipients display poor responses to SARS‐CoV‐2 mRNA vaccines. In this
retrospective study, we investigate torque teno virus (TTV) viral load (VL), a ubiquitous virus …

Torque teno virus (TTV): A gentle spy virus of immune status, predictive marker of seroconversion to COVID‐19 vaccine in kidney and lung transplant recipients

P Roberto, L Cinti, A Napoli, D Paesani… - Journal of Medical …, 2023 - Wiley Online Library
To date, no comprehensive marker to monitor the immune status of patients is available.
Given that Torque teno virus (TTV), a known human virome component, has previously been …

[HTML][HTML] Validation of plasma Torque Teno viral load applying a CE-certified PCR for risk stratification of rejection and infection post kidney transplantation

I Görzer, F Haupenthal, F Maggi, F Gelas… - Journal of Clinical …, 2023 - Elsevier
Abstract Background Torque Teno virus (TTV) is non-pathogenic, highly prevalent and
reflects the immune status of its host. TTV plasma load was suggested for risk stratification of …

[HTML][HTML] Assessment of prevalence and load of torquetenovirus viraemia in a large cohort of healthy blood donors

D Focosi, PG Spezia, L Macera, S Salvadori… - Clinical Microbiology …, 2020 - Elsevier
Objectives Torquetenovirus (TTV) is an emerging marker of functional immune competence
with the potential to predict transplant-related adverse events. A large-scale epidemiological …

[HTML][HTML] Torque teno virus in liver diseases: On the way towards unity of view

VI Reshetnyak, IV Maev, AI Burmistrov… - World journal of …, 2020 - ncbi.nlm.nih.gov
The review presents the data accumulated for more than 20 years of research of torque teno
virus (TTV). Its molecular genetic structure, immunobiology, epidemiology, diagnostic …

Smoking, Alcohol Intake and Torque Teno Virus in Stable Kidney Transplant Recipients

CSE Doorenbos, J Jonker, J Hao, EJ Gore, D Kremer… - Viruses, 2023 - mdpi.com
Torque Teno Virus (TTV) is a non-pathogenic virus that is highly prevalent among kidney
transplant recipients (KTRs). Its circulating load is associated with an immunological status …