Pharmaceutical research has successfully incorporated a wealth of molecular modeling
methods, within a variety of drug discovery programs, to study complex biological and …

Natural products have been a rich source of compounds for drug discovery. However, their
use has diminished in the past two decades, in part because of technical barriers to …

This review article focuses on pre-clinical and clinical studies with some selected Brazilian
medicinal plants in different areas of interest, conducted by research groups in Brazil and …

Cancer is a heterogeneous disease and one of the major issues of health concern,
especially for the public health system globally. Nature is a source of anticancer drugs with …

The development of new drugs will certainly benefit from an ever improving knowledge of
the living beings chemistry. However, identification of drugable molecules within the …

There has been renewed interests in the exploration of natural products (NPs) for drug
discovery, and continuous investigations of the therapeutic claims and mechanisms of …

The intrinsic value of biodiversity extends beyond species diversity, genetic heritage,
ecosystem variability and ecological services, such as climate regulation, water quality …

Drug discovery from natural sources is going through a renaissance, having spent many
decades in the shadow of synthetic molecule drug discovery, despite the fact that natural …

Background The efficiency of drug development defined as a number of successfully
launched new pharmaceuticals normalized by financial investments has significantly …

Natural products from plants, animals, marine life, fungi, bacteria, and other organisms are
an important resource for modern drug discovery. Their biological relevance and structural …