Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications

CD Spicer, C Jumeaux, B Gupta… - Chemical Society …, 2018 - pubs.rsc.org
Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …

[HTML][HTML] Nanoparticle vaccines

L Zhao, A Seth, N Wibowo, CX Zhao, N Mitter, C Yu… - Vaccine, 2014 - Elsevier
Nanotechnology increasingly plays a significant role in vaccine development. As vaccine
development orientates toward less immunogenic “minimalist” compositions, formulations …

Minireview: nanoparticles and the immune system

BS Zolnik, Á González-Fernández, N Sadrieh… - …, 2010 - academic.oup.com
Today nanotechnology is finding growing applications in industry, biology, and medicine.
The clear benefits of using nanosized products in various biological and medical …

COVID-19, an opportunity to reevaluate the correlation between long-term effects of anthropogenic pollutants on viral epidemic/pandemic events and prevalence

A Tsatsakis, D Petrakis, TK Nikolouzakis… - Food and Chemical …, 2020 - Elsevier
Occupational, residential, dietary and environmental exposures to mixtures of synthetic
anthropogenic chemicals after World War II have a strong relationship with the increase of …

Vaccine technologies: From whole organisms to rationally designed protein assemblies

CP Karch, P Burkhard - Biochemical pharmacology, 2016 - Elsevier
Vaccines have been the single most significant advancement in public health, preventing
morbidity and mortality in millions of people annually. Vaccine development has traditionally …

Nano-microparticles as immune adjuvants: correlating particle sizes and the resultant immune responses

MO Oyewumi, A Kumar, Z Cui - Expert review of vaccines, 2010 - Taylor & Francis
The development of novel immune adjuvants is emerging as a significant area of vaccine
delivery based on the continued necessity to amplify immune responses to a wide array of …

[HTML][HTML] Nano toolbox in immune modulation and nanovaccines

M Azharuddin, GH Zhu, A Sengupta, J Hinkula… - Trends in …, 2022 - cell.com
Despite the great success of vaccines over two centuries, the conventional strategy is based
on attenuated/altered microorganisms. However, this is not effective for all microbes and …

Aluminum hydroxide nanoparticles show a stronger vaccine adjuvant activity than traditional aluminum hydroxide microparticles

X Li, AM Aldayel, Z Cui - Journal of controlled release, 2014 - Elsevier
Aluminum hydroxide is used as a vaccine adjuvant in various human vaccines.
Unfortunately, despite its favorable safety profile, aluminum hydroxide can only weakly or …

[HTML][HTML] Nanoparticle vaccines adopting virus-like features for enhanced immune potentiation

S Chattopadhyay, JY Chen, HW Chen, CMJ Hu - Nanotheranostics, 2017 - ncbi.nlm.nih.gov
Synthetic nanoparticles play an increasingly significant role in vaccine design and
development as many nanoparticle vaccines show improved safety and efficacy over …

Intracellular dynamics of cationic and anionic polystyrene nanoparticles without direct interaction with mitotic spindle and chromosomes

Y Liu, W Li, F Lao, Y Liu, L Wang, R Bai, Y Zhao… - Biomaterials, 2011 - Elsevier
The fate of nanomaterials with different sizes and charges in mitotic cells is of great
importance but seldom explored. Herein we investigate the intracellular fate of negatively …