The sequence of the human genome

JC Venter, MD Adams, EW Myers, PW Li, RJ Mural… - science, 2001 - science.org
A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human
genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion …

[HTML][HTML] Olfaction: diverse species, conserved principles

BW Ache, JM Young - Neuron, 2005 - cell.com
Olfaction is a vitally important sense for all animals. There are striking similarities between
species in the organization of the olfactory pathway, from the nature of the odorant receptor …

Initial sequencing and analysis of the human genome

US DOE Joint Genome Institute: Hawkins Trevor 4 … - Nature, 2001 - nature.com
The human genome holds an extraordinary trove of information about human development,
physiology, medicine and evolution. Here we report the results of an international …

Gene conversion: mechanisms, evolution and human disease

JM Chen, DN Cooper, N Chuzhanova, C Férec… - Nature Reviews …, 2007 - nature.com
Gene conversion, one of the two mechanisms of homologous recombination, involves the
unidirectional transfer of genetic material from a'donor'sequence to a highly homologous' …

The complete human olfactory subgenome

G Glusman, I Yanai, I Rubin, D Lancet - Genome research, 2001 - genome.cshlp.org
Olfactory receptors likely constitute the largest gene superfamily in the vertebrate genome.
Here we present the nearly complete human olfactory subgenome elucidated by mining the …

Pseudogenes: are they “junk” or functional DNA?

ES Balakirev, FJ Ayala - Annual review of genetics, 2003 - annualreviews.org
▪ Abstract Pseudogenes have been defined as nonfunctional sequences of genomic DNA
originally derived from functional genes. It is therefore assumed that all pseudogene …

addendum: A universal scaling law for atomic diffusion in condensed matter

M Dzugutov - Nature, 2001 - nature.com
The human genome holds an extraordinary trove of information about human development,
physiology, medicine and evolution. Here we report the results of an international …

Human specific loss of olfactory receptor genes

Y Gilad, O Man, S Pääbo… - Proceedings of the …, 2003 - National Acad Sciences
Olfactory receptor (OR) genes constitute the basis for the sense of smell and are encoded by
the largest mammalian gene superfamily of> 1,000 genes. In humans,> 60% of these are …

The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates

S Rouquier, A Blancher… - Proceedings of the …, 2000 - National Acad Sciences
Olfactory receptors (ORs) located in the cell membrane of olfactory sensory neurons of the
nasal epithelium are responsible for odor detection by binding specific odorant ligands …

Olfactory receptors

I Gaillard, S Rouquier, D Giorgi - Cellular and Molecular Life Sciences …, 2004 - Springer
Olfaction is an ancient sensory system allowing an organism to detect chemicals in its
environment. The first step in odor transduction is mediated by binding odorants to olfactory …