Hydroxyapatite (HAp) is the major mineral constituent of vertebrate bones and teeth. It has
been well documented that HAp nanoparticles can significantly increase the biocompatibility …

Polar and charged amino acids (AAs) are heavily expressed in non-collagenous proteins
(NCPs), and are involved in hydroxyapatite (HA) mineralization in bone. Here, we review …

The history of calcium phosphates in the medicine field starts in 1769 when the first
evidence of its existence in the bone tissue is discovered. Since then, the interest for calcium …

The first part of this review looks at the fundamental properties of hydroxyapatite (HAP), the
basic mineral constituent of mammalian hard tissues, including the physicochemical …

Recent developments in biomineralization have already demonstrated that nanosized
crystals and particles play an important role in the formation of hard tissues of animals …

Nanocrystalline calcium phosphate apatites constitute the main inorganic part of hard
tissues, and a growing focus is devoted to prepare synthetic analogs, so-called “biomimetic” …

Recent developments in biomineralization have already demonstrated that nanosized
particles play an important role in the formation of hard tissues of animals. Namely, the basic …

Hydroxylapatite (or hydroxyapatite, HAp) exhibits excellent biocompatibility with various
kinds of cells and tissues, making it an ideal candidate for tissue engineering, orthopedic …

Due to a great chemical similarity with the biological calcified tissues, many calcium
orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists …

Alanine, arginine and aspartic acid have been used as co-reagents during the synthesis of a
biomimetic calcium-deficient hydroxyapatite (CDHA) for the synergistic coupling of synthesis …