Tinnitus: causes and clinical management

B Langguth, PM Kreuzer, T Kleinjung… - The Lancet …, 2013 - thelancet.com
Tinnitus is the perception of sound in the absence of a corresponding external acoustic
stimulus. With prevalence ranging from 10% to 15%, tinnitus is a common disorder. Many …

Central gain control in tinnitus and hyperacusis

BD Auerbach, PV Rodrigues, RJ Salvi - Frontiers in neurology, 2014 - frontiersin.org
Sensorineural hearing loss induced by noise or ototoxic drug exposure reduces the neural
activity transmitted from the cochlea to the central auditory system. Despite a reduced …

The neuroscience of tinnitus

JJ Eggermont, LE Roberts - Trends in neurosciences, 2004 - cell.com
Tinnitus is an auditory phantom sensation (ringing of the ears) experienced when no
external sound is present. Most but not all cases are associated with hearing loss induced …

[HTML][HTML] Advances in the neurobiology of hearing disorders: recent developments regarding the basis of tinnitus and hyperacusis

M Knipper, P Van Dijk, I Nunes, L Rüttiger… - Progress in …, 2013 - Elsevier
The prevalence of hearing problems in the Western world has, due to aging of the
population, doubled over the past 30 years. Thereby, noise-induced hearing loss is an …

An integrative model of tinnitus based on a central gain controlling neural sensitivity

AJ Noreña - Neuroscience & Biobehavioral Reviews, 2011 - Elsevier
The purpose of the current review is to propose a model highlighting the putative
connections between hearing loss and the phantom perception of tinnitus (tinnitus being …

Underlying mechanisms of tinnitus: review and clinical implications

JA Henry, LE Roberts, DM Caspary… - Journal of the …, 2014 - thieme-connect.com
Background: The study of tinnitus mechanisms has increased tenfold in the last decade. The
common denominator for all of these studies is the goal of elucidating the underlying neural …

What's the buzz? The neuroscience and the treatment of tinnitus

A Henton, T Tzounopoulos - Physiological reviews, 2021 - journals.physiology.org
Tinnitus is a pervasive public health issue that affects∼ 15% of the United States population.
Similar estimates have also been shown on a global scale, with similar prevalence found in …

Gap detection deficits in rats with tinnitus: a potential novel screening tool.

JG Turner, TJ Brozoski, CA Bauer… - Behavioral …, 2006 - psycnet.apa.org
The study describes a novel method for tinnitus screening in rats by use of gap detection
reflex procedures. The authors hypothesized that if a background acoustic signal was …

Tinnitus: models and mechanisms

JA Kaltenbach - Hearing research, 2011 - Elsevier
Over the past decade, there has been a burgeoning of scientific interest in the
neurobiological origins of tinnitus. During this period, numerous behavioral and …

Elevated fusiform cell activity in the dorsal cochlear nucleus of chinchillas with psychophysical evidence of tinnitus

TJ Brozoski, CA Bauer, DM Caspary - Journal of Neuroscience, 2002 - Soc Neuroscience
Chinchillas with psychophysical evidence of chronic tinnitus were shown to have
significantly elevated spontaneous activity and stimulus-evoked responses in putative …