Study of Genetic Mutations and Their Association With the Development of Atopic Dermatitis and Other Skin Diseases

I Hartmane - Plastic and Aesthetic Nursing, 2024 - journals.lww.com
The purpose of this study was to identify the heterogeneity of atopic dermatitis and to identify
key genetic factors. This can lead to new approaches and personalized treatment strategies …

Investigating the shared genetic architecture and causal relationship between pain and neuropsychiatric disorders

M Chen, S Li, Z Zhu, C Dai, X Hao - Human Genetics, 2023 - Springer
Pain often occurs in parallel with neuropsychiatric disorders. However, the underlying
mechanisms and potential causality have not been well studied. We collected the genome …

[HTML][HTML] Effects of nonalcoholic fatty liver disease on sarcopenia: evidence from genetic methods

J Yuan, J Zhang, Q Luo, L Peng - Scientific Reports, 2024 - nature.com
With the aging of the population, sarcopenia has become more common. Studies have
shown a broad association between liver disease and sarcopenia. However, this link …

The mental health–migration interface among sub-Saharan African and Chinese populations

AMN Renzaho, BJ Hall, W Chen - Current Opinion in Psychology, 2022 - Elsevier
This paper describes the burden of mental disorders among sub-Saharan African and
Chinese populations. Data on mental disorders in these populations provide contrasting …

[HTML][HTML] Inferring the genetic relationship between brain imaging-derived phenotypes and risk of complex diseases by Mendelian randomization and genome-wide …

S Lin, H Zhang, M Qi, DN Cooper, Y Yang, Y Yang… - NeuroImage, 2023 - Elsevier
Observational studies consistently disclose brain imaging-derived phenotypes (IDPs) as
critical markers for early diagnosis of both brain disorders and cardiovascular diseases …

[HTML][HTML] Detecting associated genes for complex traits shared across East Asian and European populations under the framework of composite null hypothesis testing

J Qiao, Z Shao, Y Wu, P Zeng, T Wang - Journal of Translational Medicine, 2022 - Springer
Background Detecting trans-ethnic common associated genetic loci can offer important
insights into shared genetic components underlying complex diseases/traits across diverse …

Genetic correlation and gene-based pleiotropy analysis for four major neurodegenerative diseases with summary statistics

J Qiao, T Wang, Z Shao, Y Zhu, M Zhang, S Huang… - Neurobiology of …, 2023 - Elsevier
Recent genome-wide association studies suggested shared genetic components between
neurodegenerative diseases. However, pleiotropic association patterns among them remain …

Maternal and fetal origins of offspring blood pressure: statistical analysis using genetic correlation and genetic risk score-based Mendelian randomization

S Jin, T Wang, C Wenying, Y Wu… - International Journal …, 2023 - academic.oup.com
Background Epidemiological studies demonstrated that adverse in utero environment was
associated with increased risk of offspring high blood pressure, by using birthweight as the …

[HTML][HTML] A comprehensive comparison of multilocus association methods with summary statistics in genome-wide association studies

Z Shao, T Wang, J Qiao, Y Zhang, S Huang, P Zeng - BMC bioinformatics, 2022 - Springer
Background Multilocus analysis on a set of single nucleotide polymorphisms (SNPs) pre-
assigned within a gene constitutes a valuable complement to single-marker analysis by …

Distal‐to‐proximal etiologically relevant variables associated with the general (p) and specific factors of psychopathology

J Ormel, M Vos, OM Laceulle, C Vrijen… - Journal of Child …, 2024 - Wiley Online Library
Background The general factor of psychopathology, often denoted as p, captures the
common variance among a broad range of psychiatric symptoms. Specific factors are co …