[HTML][HTML] From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics
Understanding how genotypes map onto phenotypes, fitness, and eventually organisms is
arguably the next major missing piece in a fully predictive theory of evolution. We refer to this …
arguably the next major missing piece in a fully predictive theory of evolution. We refer to this …
On the networked architecture of genotype spaces and its critical effects on molecular evolution
Evolutionary dynamics is often viewed as a subtle process of change accumulation that
causes a divergence among organisms and their genomes. However, this interpretation is …
causes a divergence among organisms and their genomes. However, this interpretation is …
[图书][B] Phase transitions
RV Solé - 2011 - books.google.com
Phase transitions--changes between different states of organization in a complex system--
have long helped to explain physics concepts, such as why water freezes into a solid or …
have long helped to explain physics concepts, such as why water freezes into a solid or …
Successful strategies for competing networks
Competitive interactions represent one of the driving forces behind evolution and natural
selection in biological and sociological systems,. For example, animals in an ecosystem may …
selection in biological and sociological systems,. For example, animals in an ecosystem may …
Topological structure of the space of phenotypes: the case of RNA neutral networks
The evolution and adaptation of molecular populations is constrained by the diversity
accessible through mutational processes. RNA is a paradigmatic example of biopolymer …
accessible through mutational processes. RNA is a paradigmatic example of biopolymer …
Non-Poissonian bursts in the arrival of phenotypic variation can strongly affect the dynamics of adaptation
NS Martin, S Schaper, CQ Camargo… - Molecular Biology and …, 2024 - academic.oup.com
Modeling the rate at which adaptive phenotypes appear in a population is a key to predicting
evolutionary processes. Given random mutations, should this rate be modeled by a simple …
evolutionary processes. Given random mutations, should this rate be modeled by a simple …
Virus-host protein co-expression networks reveal temporal organization and strategies of viral infection
Viral replication is a complex dynamical process involving the global remodeling of the host
cellular machinery across several stages. In this study, we provide a unified view of the virus …
cellular machinery across several stages. In this study, we provide a unified view of the virus …
Competition among networks highlights the power of the weak
The unpreventable connections between real networked systems have recently called for an
examination of percolation, diffusion or synchronization phenomena in multilayer networks …
examination of percolation, diffusion or synchronization phenomena in multilayer networks …
Thermodynamics and neutral sets in the RNA sequence-structure map
NS Martin, SE Ahnert - Europhysics Letters, 2022 - iopscience.iop.org
The sequence-structure map of biological macromolecules, also referred to as a genotype-
phenotype (GP) map, shapes evolutionary processes by determining how mutations affect …
phenotype (GP) map, shapes evolutionary processes by determining how mutations affect …
Adaptive multiscapes: an up-to-date metaphor to visualize molecular adaptation
Background Wright's metaphor of the fitness landscape has shaped and conditioned our
view of the adaptation of populations for almost a century. Since its inception, and including …
view of the adaptation of populations for almost a century. Since its inception, and including …