Autophagy, an important therapeutic target for pulmonary fibrosis diseases

H Zhao, Y Wang, T Qiu, W Liu, P Yao - Clinica chimica acta, 2020 - Elsevier
As an evolutionarily conserved intracellular degradation pathway, autophagy is essential to
cellular homeostasis. Several studies have demonstrated that autophagy showed an …

Autophagopathies: from autophagy gene polymorphisms to precision medicine for human diseases

I Grosjean, B Roméo, MA Domdom, A Belaid… - Autophagy, 2022 - Taylor & Francis
At a time when complex diseases affect globally 280 million people and claim 14 million
lives every year, there is an urgent need to rapidly increase our knowledge into their …

Diffuse pollution characteristics of respirable dust in fully-mechanized mining face under various velocities based on CFD investigation

Q Zhang, G Zhou, X Qian, M Yuan, Y Sun… - Journal of Cleaner …, 2018 - Elsevier
In order to grasp the partition diffusion and pollution of respirable dust under various
turbulent velocities in fully-mechanized mining face, Finite Volume Method was adopted to …

Numerical study of gas-solid two-phase flow around road-header drivers in a fully mechanized excavation face

S Hu, Q Liao, G Feng, Y Huang, H Shao, Y Fan, Y Ye - Powder technology, 2019 - Elsevier
It is known that high-concentrations of dust threaten the health of road-header drivers in fully
mechanized excavation faces. The regulation of the gas-solid two-phase flow in fully …

Nickel nanoparticles induce autophagy and apoptosis via HIF-1α/mTOR signaling in human bronchial epithelial cells

J Yuan, Y Mo, Y Zhang, Y Zhang, Q Zhang - Environmental Pollution, 2023 - Elsevier
With the rapid development of nanotechnology, the potential adverse health effects of
nanoparticles have been caught more attention and become global concerns. However, the …

Pathogenic single nucleotide polymorphisms on autophagy-related genes

I Tamargo-Gómez, ÁF Fernández, G Mariño - International Journal of …, 2020 - mdpi.com
In recent years, the study of single nucleotide polymorphisms (SNPs) has gained increasing
importance in biomedical research, as they can either be at the molecular origin of a …

Autophagy-related 5 gene rs510432 polymorphism is associated with hepatocellular carcinoma in patients with chronic hepatitis B virus infection

N Li, X Fan, X Wang, H Deng, K Zhang… - Immunological …, 2019 - Taylor & Francis
Background: Despite the identification of autophagy-related protein 5 (ATG5) as a molecule
involved in the activated autophagy machinery during hepatitis B virus (HBV) infection and …

Experimental study of the effects of air volume ratios on the air curtain dust cleaning in fully mechanized working face

H Wang, W Cheng, Z Sa, J Liu, R Zhang… - Journal of Cleaner …, 2021 - Elsevier
In order to fundamentally improve the dust cleaning efficiency of the fully mechanized
woking face, the effects of air volume ratios (the ratio of forced airflow volume to exhaust …

Genetic susceptibility in pneumoconiosis in China: a systematic review

SY Chair, JYW Chan, BMH Law, MMY Waye… - International Archives of …, 2023 - Springer
Objective Pneumoconiosis, encompassing coal workers' pneumoconiosis (CWP), silicosis
and asbestosis, is one of the most common occupational diseases in China. Previous …

CFD investigation on diffusing dynamics of respirable dust coupled with multiple sources on a longwall face: A case study from meso-scale

Q Zhang, X Qian, M Yuan, L Zhao, Y Zhao, T Fan… - Powder technology, 2019 - Elsevier
In order to investigate the diffusing pollution patterns of respirable dust coupled with multiple
sources in the working regions of Longwall Face, computational fluid dynamics (CFD) …