High-salt diet and hypertension: focus on the renin-angiotensin system
I Drenjančević-Perić, B Jelaković, JH Lombard… - Kidney and blood …, 2011 - karger.com
A high-salt diet is one of the major risk factors in the development and maintenance of
hypertension. Numerous experimental and observational studies have confirmed the …
hypertension. Numerous experimental and observational studies have confirmed the …
Inflammation and oxidative stress in salt sensitive hypertension; The role of the NLRP3 inflammasome
LA Ertuglu, AP Mutchler, J Yu, A Kirabo - Frontiers in Physiology, 2022 - frontiersin.org
Salt-sensitivity of blood pressure is an independent risk factor for cardiovascular disease
and affects approximately half of the hypertensive population. While the precise …
and affects approximately half of the hypertensive population. While the precise …
Natural antioxidants and hypertension: promise and challenges
TJ Kizhakekuttu, ME Widlansky - Cardiovascular therapeutics, 2010 - Wiley Online Library
Hypertension reigns as a leading cause of cardiovascular morbidity and mortality worldwide.
Excessive reactive oxygen species (ROS) have emerged as a central common pathway by …
Excessive reactive oxygen species (ROS) have emerged as a central common pathway by …
Oleuropein improves mitochondrial function to attenuate oxidative stress by activating the Nrf2 pathway in the hypothalamic paraventricular nucleus of spontaneously …
W Sun, X Wang, C Hou, L Yang, H Li, J Guo, C Huo… - …, 2017 - Elsevier
Hypertension is associated with increased reactive oxygen species (ROS) production in the
paraventricular nucleus (PVN) of the hypothalamus. Oleuropein (OL) has a variety of …
paraventricular nucleus (PVN) of the hypothalamus. Oleuropein (OL) has a variety of …
Imbalance of central nitric oxide and reactive oxygen species in the regulation of sympathetic activity and neural mechanisms of hypertension
Y Hirooka, T Kishi, K Sakai… - American Journal of …, 2011 - journals.physiology.org
Nitric oxide (NO) and reactive oxygen species (ROS) play important roles in blood pressure
regulation via the modulation of the autonomic nervous system, particularly in the central …
regulation via the modulation of the autonomic nervous system, particularly in the central …
Sympathetic activation in hypertension: importance of the central nervous system
Y Hirooka - American Journal of Hypertension, 2020 - academic.oup.com
The sympathetic nervous system plays a critical role in the pathogenesis of hypertension.
The central nervous system (CNS) organizes the sympathetic outflow and various inputs …
The central nervous system (CNS) organizes the sympathetic outflow and various inputs …
Oxidative Stress and Central Cardiovascular Regulation–Pathogenesis of Hypertension and Therapeutic Aspects–
Y Hirooka, Y Sagara, T Kishi, K Sunagawa - Circulation Journal, 2010 - jstage.jst.go.jp
HIROOKA Y et al. rats. In addition, superoxide dismutase (SOD) expression and activity,
which are ROS scavenging factors, were decreased in the RVLM of SHRSP compared with …
which are ROS scavenging factors, were decreased in the RVLM of SHRSP compared with …
Brain stem NOS and ROS in neural mechanisms of hypertension
Significance: There is now compelling evidence to substantiate the notion that by
depressing baroreflex regulation of blood pressure and augmenting central sympathetic …
depressing baroreflex regulation of blood pressure and augmenting central sympathetic …
Selective Nrf2 Gene Deletion in the Rostral Ventrolateral Medulla Evokes Hypertension and Sympathoexcitation in Mice
L Gao, MC Zimmerman, S Biswal, IH Zucker - Hypertension, 2017 - Am Heart Assoc
Nuclear factor erythroid 2–related factor 2 (Nrf2) is a master transcriptional regulator of redox
homeostasis that impacts antioxidant gene expression. Central oxidative stress and reduced …
homeostasis that impacts antioxidant gene expression. Central oxidative stress and reduced …
[HTML][HTML] Diet and primary prevention of stroke: Systematic review and dietary recommendations by the ad hoc Working Group of the Italian Society of Human Nutrition
L Iacoviello, M Bonaccio, G Cairella, MV Catani… - Nutrition, Metabolism …, 2018 - Elsevier
Background and aims To systematically review the latest evidence on established and
emerging nutrition-related risk factors for incidence of and mortality from total, ischemic and …
emerging nutrition-related risk factors for incidence of and mortality from total, ischemic and …